Anti-Influenza A Matrix 1 (M1) [1G1A12] Antibody

This mouse IgG1 mouse monoclonal antibody was raised against recombinant GST-M1 fusion protein and is specific for influenza A virus M1 protein.

Highlights:

  • Reacts with M1 protein of Influenza virus
  • Suitable for Western Blot and Immunofluorscence applications

The matrix 1 (M1) protein of the influenza A virus forms a coat inside the viral envelope and is the most abundant protein in virions. The M1 protein of influenza A virus has multiple regulatory functions during the infectious cycle and these include mediation of nuclear export of viral ribonucleoproteins, inhibition of viral transcription and a crucial role in virus assembly and budding.

From the laboratory of A*STAR Institute of Molecular and Cell Biology (IMCB) Monoclonal Antibody Unit.

Catalog Number Product Size AVAILABILITY Price Qty
ESG007
Anti-Influenza A Matrix 1 (M1) [1G1A12] Antibody
5mL supernatant 3-5 weeks
Regular Price:$250.00
Specifications

Product Type: Antibody
Antigen: M1 protein of Influenza A virus
Molecular Weight: 28 kDa
Isotype: IgG1
Clonality: Monoclonal
Clone Name: 1G1A12
Reactivity: Influenza A virus
Immunogen: Recombinant GST-M1 fusion protein
Species Immunized: Mouse
Buffer: Cell culture supernatant
Tested Applications: WB, IF, ELISA
Storage: 80C
Shipped: Dry Ice

Data

Immunofluorescence

COS-7 cells were transfected with a plasmid containing the M1 open reading frame. Cells were fixed with 4% paraformaldehyde, permeabilized with 0.1% Triton X-100 and stained with anti-M1 monoclonal antibody (mAb) and followed by secondary goat antimouse FITC (lower panel).

References
  1. Barnwal B, Mok CK, Wu J, Diwakar MK, Gupta G, Zeng Q, Chow VT, Song J, Yuan YA, Tan YJ. A monoclonal antibody binds to threonine 49 in the non-structural 1 protein of influenza A virus and interferes with its ability to modulate viral replication. Antiviral Res. 2015 Apr;116:55-61.

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