RPE is a highly selective, sensitive and reversible off-on fluorescent Fe3+ sensor which can selectively image native Fe3+ in live cells.
RPE is a highly sensitive, highly selective and reversible turn-on fluorescent Fe3+ sensor. The sensor readily detects endogenous chelatable Fe3+ in live human SH-SY5Y cells at subcellular resolution in real time. The sensor gives a distinct rapid and reversible fluorescence response upon the alteration of intracellular Fe3+ levels with little interference from other biologically relevant metal ions.
From the laboratory of Maolin Guo, PhD, University of Massachusetts Dartmouth.
|Product Type:||Small Molecule|
|Name:||Methyl 6-(3',6'-bis(diethylamino)-3-oxospiro[isoindoline-1,9'-xanthen]-2-yl)picolinate (RPE)|
|Solubility:||DMSO, DMF, EtOH, ACN, etc.|
|Spectral Information:||NMR, MS|
|Compatible Cells:||Mammalian cells|
|Detection Method:||Fluorescence (excitation: 510-580 nm; emission: 550-700 nm)|
|Comments:||Avoid exposure to light; Suggested amount per experiment: 10 μM (or 0.1 μg)|
|Storage:||-20C to -80C|
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