The AbC1 hamster melanoma line was established in 1986 from the transplantable amelanotic Bomirski melanoma in hamster that in vivo is characterized by an undifferentiated phenotype and high growth rate.
Amelanotic melanoma is a type of skin cancer in which the cells do not make melanin. They can be pink, red, purple or of normal skin color, hence difficult to recognise. It has an asymmetrical shape, and an irregular faintly pigmented border. This type of melanoma can be difficult to detect and ususally are well past stage I, which makes them more difficult to treat.
From the laboratory of Andrzej T. Slominski, MD, PhD, University of Alabama at Birmingham.
|Product Type:||Cell Line|
|Growth Conditions:||Ham's F-10 media, 1% antibiotic and antimyotic, 5% FBS|
|Cryopreservation:||Media + 10% DMSO|
|Comments:||Cells can grow in Ham’s F10 medium plus either 5% or 10% serum to maintain amelanotic phenotype|
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