Anti-ADAR2 (ADARB1) [1.3.1] Antibody

This mouse IgG monoclonal antibody was raised against purified GST-double-stranded RNA-specific editase 1 (ADAR2a) fusion protein (N-terminal Region, Amino Acids 2-179) and recognizes human and mouse ADAR2.

Highlights:

  • Reacts with human and mouse ADAR2
  • Does not cross-react with different members of the ADAR family
  • Suitable for Western Blot, Immunohistochemistry and Immunostaining applications

ADAR2 or ADARB1 encodes the enzyme responsible for pre-mRNA editing of the glutamate receptor subunit B by site-specific deamination of adenosines. Studies in rat found that this enzyme acted on its own pre-mRNA molecules to convert an AA dinucleotide to an AI dinucleotide which resulted in a new splice site. Alternative splicing of this gene results in several transcript variants, some of which have been characterized by the presence or absence of an ALU cassette insert and a short or long C-terminal region.

From the laboratory of Kazuko Nishikura, PhD, The Wistar Institute.

Catalog Number Product DataSheet Size AVAILABILITY Price Qty
EWI037
Anti-ADAR2 (ADARB1) [1.3.1] Antibody
100ug 4-6 weeks
Regular Price:$299.00
On Sale:
Specifications

Product Type: Antibody
Accession ID: NCBI Gene ID: 104, Protein Accession No.: NP 056648
Antigen: ADAR2 (ADARB1; adenosine deaminase, RNA specific B1)
Molecular Weight: 90 kDa
Isotype: IgG
Clonality: Monoclonal
Clone Name: 1.3.1
Specificity: Native and Recombinant ADAR2; does not cross-react with different members of the ADAR family
Reactivity: Human and mouse
Immunogen: N-terminal, raised Against Purified GST-ADAR2a Fusion Protein (N-terminal Region, Amino Acids 2-179)
Species Immunized: Mouse
Purification Method: Protein G
Buffer: PBS, 0.05% (w/v) Sodium Azide
Tested Applications: WB, IHC, Immunostaining
Storage: -20C
Shipped: Cold Packs

Provider
From the laboratory of Kazuko Nishikura, PhD, The Wistar Institute.

References
  1. Cho DS, Yang W, Lee JT, Shiekhattar R, Murray JM, Nishikura K. Requirement of dimerization for RNA editing activity of adenosine deaminases acting on RNA. J Biol Chem. 2003 May 9;278(19):17093-102. Epub 2003 Mar 4. PubMed PMID: 12618436.

If you publish research with this product, please let us know so we can cite your paper.

Loading...