This mouse IgG2a kappa monoclonal antibody was generated against full length protein with C-terminal 6xHis-tag and is specific for human C-terminal-binding protein 1 (CTBP1).
CtBP1 is broadly expressed from embryo to adult, and functions as a transcriptional compressor. Transciptional compressors are regulatory proteins that bind to sequence-specific DNA-binding proteins and help turn genes off. CtBPs have multiple biological roles and appear to be most important in regulating the epithelial to mesenchymal transition, as well as influencing metabolism.
From the laboratory of Steven R. Grossman, MD, PhD, Virginia Commonwealth University.
|Antigen:||Full length protein with C-terminal 6xHis-tag|
|Molecular Weight:||45-48 kDa|
|Reactivity:||Human (others not tested)|
|Immunogen:||Full length protein with C-terminal 6xHis-tag|
|Buffer:||PBS + 0.05% NaN3|
|Tested Applications:||WB, IP, IFC, CHIP|
|Comments:||CTBP1 specific, does not cross-react with CTBP2|
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