Anti-Methylenetetrahydrofolate Reductase (MTFR) Antibody

This rabbit polyclonal antibody was generated against recombinant protein and recognizes human and mouse methylenetetrahydrofolate reductase (MTHFR).


  • Reacts with human and mouse MTHFR
  • Suitable for Western Blot applications

Methylenetetrahydrofolate reductase is an enzyme that catalyzes the conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a co-substrate for homocysteine remethylation to methionine. Variations in this protein have been shown to be related to occlusive vascular disease, neural tube defects, Alzeimer's, colon cancer and leukemia.

From the laboratory of Rima Rozen, PhD, McGill University.

Catalog Number Product DataSheet Size AVAILABILITY Price Qty
Anti-Methylenetetrahydrofolate Reductase (MTFR) Antibody
100uL In stock
Regular Price:$345.00
On Sale:

Product Type: Antibody
Antigen: Methylenetetrahydrofolate reductase (MTHFR)
Accession ID: P42898
Molecular Weight: ~77 and 70 kDa
Clonality: Polyclonal
Reactivity: Human and Mouse
Immunogen: Recombinant protein
Species Immunized: Rabbit
Purification Method: Unpurified serum
Buffer: Serum
Tested Applications: WB (1:2000)
Storage: -80C
Shipped: Cold Packs (Domestic, Overnight); Dry Ice (International)

From the laboratory of Rima Rozen, PhD, McGill University.
  1. Tran P, Leclerc D, Chan M, Pai A, Hiou-Tim F, Wu Q, Goyette P, Artigas C, Milos R, Rozen R. Multiple transcription start sites and alternative splicing in the methylenetetrahydrofolate reductase gene result in two enzyme isoforms. Mamm Genome. 2002 Sep;13(9):483-92.
  2. Mikael LG, Rozen R. Homocysteine modulates the effect of simvastatin on expression of ApoA-I and NF-kappaB/iNOS. Cardiovasc Res. 2008 Oct 1;80(1):151-8. doi: 10.1093/cvr/cvn157. Epub 2008 Jun 7.

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