Anti-Methylenetetrahydrofolate Reductase (MTFR) Antibody
This rabbit polyclonal antibody was generated against recombinant protein and recognizes human and mouse methylenetetrahydrofolate reductase (MTHFR).
Highlights:
- Reacts with human and mouse MTHFR
- Suitable for Western Blot applications
Methylenetetrahydrofolate reductase is an enzyme that catalyzes the conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a co-substrate for homocysteine remethylation to methionine. Variations in this protein have been shown to be related to occlusive vascular disease, neural tube defects, Alzeimer's, colon cancer and leukemia.
From the laboratory of Rima Rozen, PhD, McGill University.
This rabbit polyclonal antibody was generated against recombinant protein and recognizes human and mouse methylenetetrahydrofolate reductase (MTHFR).
Highlights:
- Reacts with human and mouse MTHFR
- Suitable for Western Blot applications
Methylenetetrahydrofolate reductase is an enzyme that catalyzes the conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a co-substrate for homocysteine remethylation to methionine. Variations in this protein have been shown to be related to occlusive vascular disease, neural tube defects, Alzeimer's, colon cancer and leukemia.
From the laboratory of Rima Rozen, PhD, McGill University.
Specifications
| Product Type: | Antibody |
| Antigen: | Methylenetetrahydrofolate reductase (MTHFR) |
| Accession ID: | P42898 |
| Molecular Weight: | ~77 and 70 kDa |
| Clonality: | Polyclonal |
| Reactivity: | Human and Mouse |
| Immunogen: | Recombinant protein |
| Species Immunized: | Rabbit |
| Purification Method: | Unpurified serum |
| Buffer: | Serum |
| Tested Applications: | WB (1:2000) |
| Storage: | -80C |
| Shipped: | Cold Packs (Domestic, Overnight); Dry Ice (International) |
Provider
From the laboratory of Rima Rozen, PhD, McGill University.
References
- Tran P, Leclerc D, Chan M, Pai A, Hiou-Tim F, Wu Q, Goyette P, Artigas C, Milos R, Rozen R. Multiple transcription start sites and alternative splicing in the methylenetetrahydrofolate reductase gene result in two enzyme isoforms. Mamm Genome. 2002 Sep;13(9):483-92.
- Mikael LG, Rozen R. Homocysteine modulates the effect of simvastatin on expression of ApoA-I and NF-kappaB/iNOS. Cardiovasc Res. 2008 Oct 1;80(1):151-8. doi: 10.1093/cvr/cvn157. Epub 2008 Jun 7.
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