This rabbit polyclonal antibody was generated against recombinant human iron regulatory protein 1 (IRP1) and recognizes human and mouse IRP1 .
IRP1 stands for “iron regulatory protein 1”. It is encoded by the ACO1 gene (aconitase 1). IRP1 is a soluble protein and an iron sensor. When cellular iron levels are high, this protein binds to a 4Fe-4S cluster and functions as an aconitase. Aconitases are iron-sulfur proteins that function to catalyze the conversion of citrate to isocitrate.
From the laboratory of Kostas Pantopoulos, PhD, McGill University.
|Molecular Weight:||100 kDa|
|Reactivity:||Human and Mouse|
|Immunogen:||Recombinant human IRP1|
|Epitope:||Full length IRP1|
|Buffer:||Serum with 0.05% sodium azide|
|Tested Applications:||WB (1:2000) and IP|
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