Anti-Aconitase (ACO1/IRP1) Antibody

This rabbit polyclonal antibody was generated against recombinant human iron regulatory protein 1 (IRP1) and recognizes human and mouse IRP1 .

Highlights:

  • Reacts with human and mouse, full-length IRP1
  • Suitable for Western Blot and Immunoprecipitation applications

IRP1 stands for “iron regulatory protein 1”. It is encoded by the ACO1 gene (aconitase 1). IRP1 is a soluble protein and an iron sensor. When cellular iron levels are high, this protein binds to a 4Fe-4S cluster and functions as an aconitase. Aconitases are iron-sulfur proteins that function to catalyze the conversion of citrate to isocitrate.

From the laboratory of Kostas Pantopoulos, PhD, McGill University.

Catalog Number Product DataSheet Size AVAILABILITY Price Qty
EMG012
Anti-Aconitase (ACO1/IRP1) Antibody
100uL In stock
Regular Price:$299.00
On Sale:
Specifications

Product Type: Antibody
Accession ID: P21399
Antigen: Human IRP1
Molecular Weight: 100 kDa
Clonality: Polyclonal
Reactivity: Human and Mouse
Immunogen: Recombinant human IRP1
Species Immunized: Rabbit
Epitope: Full length IRP1
Purification Method: Serum
Buffer: Serum with 0.05% sodium azide
Tested Applications: WB (1:2000) and IP
Storage: -80C
Shipped: Dry Ice

Provider
From the laboratory of Kostas Pantopoulos, PhD, McGill University.
References
  1. Fillebeen C, Chahine D, Caltagirone A, Segal P, Pantopoulos K. A phosphomimetic mutation at Ser-138 renders iron regulatory protein 1 sensitive to iron-dependent degradation. Mol Cell Biol. 2003 Oct;23(19):6973-81.

If you publish research with this product, please let us know so we can cite your paper.

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