Anti-Nidogen, G2 Region [5G12-D4-E3] Antibody

This rat IgG2b monoclonal antibody was generated against G2 region of mouse nidogen and recognizes nidogen.

Highlights:

  • Reacts with nidogen
  • Able to block nidogen binding to laminin
  • Suitable for Western Blot and ELISA applications

Nidogens, formerly known as entactins, are a family of sulfated monomeric glycoproteins located in the basal lamina. There are two types, nidogen-1 (NID1) and nidogen-2 (NID2). The basement membrane protein, nidogen-1, was previously shown to consist of three globular domains, G1 to G3, and two connecting segments. Nidogen-1 is a major mediator in the formation of ternary complexes with laminins, collagen IV, perlecan and fibulins. Nidogens have been shown to play a role in cardiac and lung development.

From the laboratory of Jay W. Fox, PhD, University of Virginia.

Catalog Number Product Size AVAILABILITY Price Qty
EG1016
Anti-Nidogen, G2 Region [5G12-D4-E3] Antibody
100ug 3-5 weeks
Regular Price:$299.00
Specifications

Product Type: Antibody
Antigen: Nidogen
Isotype: IgG2b
Clonality: Monoclonal
Clone Name: 5G12-D4-E3
Immunogen: G2 region of mouse nidogen
Species Immunized: Rat
Purification Method: Protein G
Buffer: 0.1M Sodium Phosphate, pH 7.4, 0.15M NaCl, 0.05% (w/v) Sodium Azide
Tested Applications: WB, ELISA
Storage: -20C
Shipped: Cold Packs

Provider
From the laboratory of Jay W. Fox, PhD, University of Virginia.

References
  1. Ries A, Göhring W, Fox JW, Timpl R, Sasaki T. Recombinant domains of mouse nidogen-1 and their binding to basement membrane proteins and monoclonal antibodies. Eur J Biochem. 2001 Oct;268(19):5119-28. PubMed PMID: 11589703.

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