Anti-Ceacam 2 [2052/2053] Antibody
![Anti-Ceacam 2 [2052/2053] Antibody](https://www.kerafast.com/MediaStorage/Product/Images/Large/1614_2001202001265416130.jpg "Anti-Ceacam 2 [2052/2053] Antibody")
This rabbit polyclonal antibody was generated against carcinoembryonic antigen-related cell adhesion molecule 2 (CEACAM2)-His-tagged purified protein from baculovirus-infected transfected cells, protein fully glycosylated and is specific for mouse CEACAM2.
Highlights:
- Specific for mouse CEACAM2; Does not react with other species
- Reacts with N-terminal domain and A domain of mouse CEACAM2
- Suitable for Western Blot, Immunoprecipitation, Immunofluorescence and Immunohistochemistry applications
CEACAM2 (biliary glycoprotein) has shown to be involved in energy balance and peripheral insulin action. Also involved in regulation of feeding behavior particularly in the ventromedial nucleus of hypothalamus (VMH) regulation of food intake. CEACAM2 has a role in the regulation of metabolic rate and insulin sensitivity or resistance via effects on brown adipogenesis, sympathetic nervous outflow to brown adipose tissue, spontaneous activity and energy expenditure in skeletal muscle. In case of murine coronavirus (MHV) infection, does probably not serve as functional receptor for the virus. Similar to CEACAM1, it also contributes to cell to cell adhesion.
From the laboratory of Nicole Beauchemin, PhD, McGill University.
This rabbit polyclonal antibody was generated against carcinoembryonic antigen-related cell adhesion molecule 2 (CEACAM2)-His-tagged purified protein from baculovirus-infected transfected cells, protein fully glycosylated and is specific for mouse CEACAM2.
Highlights:
- Specific for mouse CEACAM2; Does not react with other species
- Reacts with N-terminal domain and A domain of mouse CEACAM2
- Suitable for Western Blot, Immunoprecipitation, Immunofluorescence and Immunohistochemistry applications
CEACAM2 (biliary glycoprotein) has shown to be involved in energy balance and peripheral insulin action. Also involved in regulation of feeding behavior particularly in the ventromedial nucleus of hypothalamus (VMH) regulation of food intake. CEACAM2 has a role in the regulation of metabolic rate and insulin sensitivity or resistance via effects on brown adipogenesis, sympathetic nervous outflow to brown adipose tissue, spontaneous activity and energy expenditure in skeletal muscle. In case of murine coronavirus (MHV) infection, does probably not serve as functional receptor for the virus. Similar to CEACAM1, it also contributes to cell to cell adhesion.
From the laboratory of Nicole Beauchemin, PhD, McGill University.
| Product Type: | Antibody |
| Antigen: | CEACAM2 |
| Accession ID: | X76085 |
| Molecular Weight: | Native protein: CEACAM2 (33 kDa) |
| Clonality: | Polyclonal |
| Clone Name: | 2052/2053 |
| Reactivity: | Mouse |
| Immunogen: | CEACAM2-His-tagged purified protein from baculovirus-infected transfected cells, protein fully glycosylated |
| Species Immunized: | Rabbit |
| Epitope: | N-terminal domain and A domain of mouse CEACAM2 |
| Buffer: | Serum |
| Tested Applications: | WB (1:1000 with ECL detection), IP (IP (10 ul of Ab for IP of CEACAM2 from 1 mg of total lysate protein from transfected cells), IF (1:500), IHC (1:250-1:500) |
| Storage: | -80C |
| Shipped: | Cold Packs (Domestic, Overnight); Dry Ice (International) |
- Robitaille J, Izzi L, Daniels E, Zelus B, Holmes KV, Beauchemin N. Comparison of expression patterns and cell adhesion properties of the mouse biliary glycoproteins Bbgp1 and Bbgp2. Eur J Biochem. 1999 Sep;264(2):534-44. PubMed PMID: 10491101.
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