Anti-Cytochrome P450 2J2 (CYP2J2) Antibody

This rabbit polyclonal antibody was generated against a peptide and recognizes human, mouse and rat cytochrome P450 2J subfamily enzymes including human CYP2J2


  • Reacts with human, mouse and rat CYP2J subfamily enzymes
  • Suitable for Western Blot and Immunohistochemistry applications

CYP2J2 is an enzyme that metabolizes arachidonic acid predominantly via NADPH-dependent olefin epoxidation to all four regioisomeric cis-epoxyeicosatrienoic acids. It is responsible for the epoxidation of endogenous cardiac arachidonic acid pools. CYP2J2 contains 3 different domains; a hydrophobic domain, an F-G loop primary membrane binding motif, and an N-terminal anchor domain. CYP2J2 has been shown to be overexpressed in a number of cancers and forced overexpression of CYP2J2 in human cancer cells lines accelerated proliferation and protected the cells against apopotosis.

From the laboratory of Darryl C. Zeldin, MD, National Institute of Environmental Health Sciences/NIH.

Catalog Number Product DataSheet Size AVAILABILITY Price Qty
Anti-Cytochrome P450 2J2 (CYP2J2) Antibody
50uL In stock
Regular Price:$345.00
On Sale:

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Product Type: Antibody
Antigen: CYP2J specific peptide
Accession ID: P51589
Molecular Weight: ~57 kDa
Clonality: Polyclonal
Clone Name: CYP2J2
Reactivity: Mouse/human/rat
Immunogen: Peptide
Species Immunized: Rabbit
Buffer: Antiserum
Tested Applications: WB (1:2000), IHC (1:8000)
Storage: -80C
Shipped: Cold Packs (Domestic, Overnight); Dry Ice (International)


Western Blot

CYP2Js expressed in Sf21 insect cells, lanes 1 to 7, and CYP2Cs expressed in E. Coli, lanes 8-10, were probed with anti-CYP2J2pep3 (1:2000). Proteins were visualized using a Goat Anti-Rabbit IgG secondary antibody conjugated to HRP (Calbiochem cat # 401315, 1:3000) and a chemiluminescence detection system.

From the laboratory of Darryl C. Zeldin, MD, National Institute of Environmental Health Sciences/NIH.

  1. Yaghi A, Bradbury JA, Zeldin DC, Mehta S, Bend JR, McCormack DG. Pulmonary cytochrome P-450 2J4 is reduced in a rat model of acute Pseudomonas pneumonia. Am J Physiol Lung Cell Mol Physiol. 2003 Nov;285(5):L1099-105. Epub 2003 Jul 25. PubMed PMID: 12882760.

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