This mouse IgG2a monoclonal antibody recognizes human and mouse apoptosis RNA-binding protein FUS (FUS/TLS).
RNA-binding protein FUS binds both single-stranded and double-stranded DNA and promotes ATP-independent annealing of complementary single-stranded DNAs and D-loop formation in superhelical double-stranded DNA. It also has shown to play a role in maintenance of genomic integrity. FUS/TLS has been associated with liposarcoma, a cancer that arises in fat cells in deep soft tissue.
From the laboratory of Marko Radic, PhD, University of Tennessee.
|Molecular Weight:||65 kDa|
|Reactivity:||Human and mouse|
|Purification Method:||Protein G|
|Buffer:||PBS, 0.05% (w/v) Sodium Azide|
|Tested Applications:||WB, IF|
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