Anti-HPV18, Protein E7 [HPV E7-99] Antibody

This mouse monoclonal antibody was generated against E7 proteins of human papillomavirus type 18 (HPV18) and recognizes E7 protein of HPV18 and HPV16


  • Readily detects HPV
  • Reacts with E7 protein from HPV18 and HPV16
  • Suitable for Western Blot, ELISA, Immunofluorescence, Immunohistochemistry applications

Protein E7 plays a role in HPV viral genome replication by driving entry of quiescent cells into the cell cycle. Stimulation of progression from G1 to S phase allows the virus to efficiently use the cellular DNA replicating machinery to achieve viral genome replication. E7 protein has both transforming and trans-activating activities. E7 induces the disassembly of the E2F1 transcription factor from RB1, with subsequent transcriptional activation of E2F1-regulated S-phase genes. E7 interferes with host histone deacetylation mediated by HDAC1 and HDAC2, leading to transcription activation. E7 also plays a role in the inhibition of both antiviral and antiproliferative functions of host inteferon alpha.

From the laboratory of A. Bennett Jenson, MD and Shin Je Ghim, PhD, University of Louisville.

Catalog Number Product DataSheet Size AVAILABILITY Price Qty
Anti-HPV18, Protein E7 [HPV E7-99] Antibody
100ug In stock
Regular Price:$355.00
On Sale:

Product Type: Antibody
Name: Anti-HPV18, Protein E7 [HPV E7-99] Antibody
Accession ID: NC_001357; P06788
Antigen: Major capsid protein of Human papillomavirus type 18
Molecular Weight: 17 kDa
Clonality: Monoclonal
Clone Name: HPV E7-99
Reactivity: Viral protein
Immunogen: E7 proteins of HPV18 (E7 fusion Protein was cleaved and purified)
Species Immunized: BALB/c mouse
Epitope: Epitopes are on E7 of Both HPV16 and 18
Purification Method: Protein A/G Chromatography
Buffer: 0.1M Sodium Phosphate, pH 7.4, 0.15M NaCl, 0.05% (w/v) Sodium Azide
Tested Applications: WB, ELISA, IF, immunohistochemistry
Storage: -20C
Shipped: Cold packs

From the laboratory of A. Bennett Jenson, MD and Shin Je Ghim, PhD, , University of Louisville.

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