This mouse monoclonal antibody was generated against and recognize streptavidin.
Streptavidin is widely used in biotechnology and molecular research for detection, purification, crosslinking, and labeling of biotinylated targets. However, wild-type streptavidin is an obligate tetramer and can crosslink biotinylated targets. Target aggregation is a significant obstacle in some applications, including the labeling of biotinylated cell surface receptors, where crosslinking can perturb protein stability and function.
From the laboratory of Ann M. Rothstein, PhD, University of Massachusetts Medical School.
|Species Immunized:||Balb/c mice|
|Purification Method:||Protein A-Agarose|
|Buffer:||0.1M Sodium Phosphate, pH 7.4, 0.15M NaCl, 0.05% (w/v) Sodium Azide|
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