Anti-Bone Sialoprotein (BSP), A129-I139 [LF-100] Antibody

This rabbit IgG polyclonal antibody was generated against peptide and recognizes human, monkey, dog, and rat bone sialoprotein (BSP).

Highlights:

  • Recognizes human, monkey, dog, and rat BSP- Epitope AIQLPKKAGDI
  • Suitable for Immunohistochemistry and Western Blot applications

Bone sialoprotein (BSP) is a component of tissues such as bone, dentin, cementum and calcified cartilage. BSP is a phosphorylated glycoprotein and has been found in cells such as osteoblasts and osteocytes. Bone sialoprotein could be a potential serum marker for monitoring bone remodelling.

From the laboratory of Larry W. Fisher, PhD, National Institute of Dental and Craniofacial Research/NIH.

Catalog Number Product DataSheet Size AVAILABILITY Price Qty
ENH074-FP
Anti-Bone Sialoprotein (BSP), A129-I139 [LF-100] Antibody
100uL In stock
Regular Price:$306.00
On Sale:

This product is for sale to Nonprofit customers only. For profit customers, please Contact Us for more information.

Specifications

Product Type: Antibody
Antigen: Bone Sialoprotein (BSP), human
Accession ID: NP_004958.2
Molecular Weight: 35148 Da
Clonality: Polyclonal
Clone Name: LF-100
Reactivity: Human, monkey, dog, rat
Immunogen: Peptide
Species Immunized: Rabbit
Epitope: AIQLPKKAGDI
Buffer: Whole serum
Tested Applications: WB 1:2000, IHC 1:200
Storage: -80C
Shipped: Dry Ice

Provider
From the laboratory of Larry W. Fisher, PhD, National Institute of Dental and Craniofacial Research.
References
  1. Fisher LW, Stubbs JT 3rd, Young MF. Antisera and cDNA probes to human and certain animal model bone matrix noncollagenous proteins. Acta Orthop Scand Suppl. 1995 Oct;266:61-5. PubMed PMID: 8553864.
  2. Waltregny D, Bellahcène A, Van Riet I, Fisher LW, Young M, Fernandez P, Dewé W, de Leval J, Castronovo V. Prognostic value of bone sialoprotein expression in clinically localized human prostate cancer. J Natl Cancer Inst. 1998 Jul 1;90(13):1000-8. PubMed PMID: 9665149.
  3. Fedarko NS, Fohr B, Robey PG, Young MF, Fisher LW. Factor H binding to bone sialoprotein and osteopontin enables tumor cell evasion of complement-mediated attack. J Biol Chem. 2000 Jun 2;275(22):16666-72.
  4. Jain A, Karadag A, Fisher LW, Fedarko NS. Structural requirements for bone sialoprotein binding and modulation of matrix metalloproteinase-2. Biochemistry. 2008 Sep 23;47(38):10162-70.
  5. Gronthos S, Mankani M, Brahim J, Robey PG, Shi S. Postnatal human dental pulp stem cells (DPSCs) in vitro and in vivo. Proc Natl Acad Sci U S A. 2000 Dec 5;97(25):13625-30. PubMed PMID: 11087820; PubMed Central PMCID: PMC17626.
  6. Gorski JP, Huffman NT, Cui C, Henderson EP, Midura RJ, Seidah NG. Potential role of proprotein convertase SKI-1 in the mineralization of primary bone. Cells Tissues Organs. 2009;189(1-4):25-32. doi: 10.1159/000151723. Epub 2008 Aug 26. PubMed PMID: 18728345; PubMed Central PMCID: PMC2824183.
  7. Petri AD, Teixeira LN, Crippa GE, Beloti MM, de Oliveira PT, Rosa AL. Effects of low-level laser therapy on human osteoblastic cells grown on titanium. Braz Dent J. 2010;21(6):491-8. PubMed PMID: 21271038.

If you publish research with this product, please let us know so we can cite your paper.

Loading...