Anti-Decorin (human) [LF-122] Antibody
![Anti-Decorin (human) [LF-122] Antibody](https://www.kerafast.com/MediaStorage/Product/Images/Large/1519_2001202001265115180.jpg "Anti-Decorin (human) [LF-122] Antibody")
This rabbit IgG polyclonal antibody was generated against recombinat protein E. coli and recognizes human, sheep and pig decorin.
Highlights:
- Recognizes human, sheep and pig decorin
- Suitable for Immunohistochemistry and Western Blot applications
Decorin belongs to the small leucine-rich repeat proteoglycan (SLRP) family which is found in a variety of extracellular matrix tissues, including bone, cartilage and tendon. In humans it is encoded by the DCN gene and is mainly involved in collagen fiber assembly.
From the laboratory of Larry W. Fisher, PhD, National Institute of Dental and Craniofacial Research/NIH.
This rabbit IgG polyclonal antibody was generated against recombinat protein E. coli and recognizes human, sheep and pig decorin.
Highlights:
- Recognizes human, sheep and pig decorin
- Suitable for Immunohistochemistry and Western Blot applications
Decorin belongs to the small leucine-rich repeat proteoglycan (SLRP) family which is found in a variety of extracellular matrix tissues, including bone, cartilage and tendon. In humans it is encoded by the DCN gene and is mainly involved in collagen fiber assembly.
From the laboratory of Larry W. Fisher, PhD, National Institute of Dental and Craniofacial Research/NIH.
This product is for sale to Nonprofit customers only. For profit customers, please Contact Us for more information.
Specifications
| Product Type: | Antibody |
| Antigen: | Decorin, human |
| Accession ID: | P07585 |
| Molecular Weight: | 39747 Da |
| Clonality: | Polyclonal |
| Clone Name: | LF-122 |
| Reactivity: | Human, sheep, pig |
| Immunogen: | Recombinant E. coli |
| Species Immunized: | Rabbit |
| Buffer: | Whole serum |
| Tested Applications: | WB 1:2000, IHC 1:200 |
| Comments: | Core protein should appear on westerns after digestion with chondroitinase ABC |
| Storage: | -80C |
| Shipped: | Cold Packs (Domestic, Overnight); Dry Ice (International) |
Provider
From the laboratory of Larry W. Fisher, PhD, National Institute of Dental and Craniofacial Research.
References
- Fisher LW, Stubbs JT 3rd, Young MF. Antisera and cDNA probes to human and certain animal model bone matrix noncollagenous proteins. Acta Orthop Scand Suppl. 1995 Oct;266:61-5. PubMed PMID: 8553864.
- Neufeld EB, Zadrozny LM, Phillips D, Aponte A, Yu ZX, Balaban RS. Decorin and biglycan retain LDL in disease-prone valvular and aortic subendothelial intimal matrix. Atherosclerosis. 2014 Mar;233(1):113-21.
- JWilson CG, Nishimuta JF, Levenston ME. Chondrocytes and meniscal fibrochondrocytes differentially process aggrecan during de novo extracellular matrix assembly. Tissue Eng Part A. 2009 Jul;15(7):1513-22.
- von Marschall Z, Fisher LW. Decorin is processed by three isoforms of bone morphogenetic protein-1 (BMP1). Biochem Biophys Res Commun. 2010 Jan 15;391(3):1374-8.
- Bredrup C, Stang E, Bruland O, Palka BP, Young RD, Haavik J, Knappskog PM, Rødahl E. Decorin accumulation contributes to the stromal opacities found in congenital stromal corneal dystrophy. Invest Ophthalmol Vis Sci. 2010 Nov;51(11):5578-82.
- Merrilees MJ, Ching PS, Beaumont B, Hinek A, Wight TN, Black PN. Changes in elastin, elastin binding protein and versican in alveoli in chronic obstructive pulmonary disease. Respir Res. 2008 May 18;9:41.
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