Anti-Dentin Sialophosphoprotein (DSPP), human DSP/DPP domains [LF-154] Antibody

This rabbit IgG polyclonal antibody was generated against recombinant protein (E coli) and is specific for human Dentin Sialophosphoprotein (DSPP).

Highlights:

  • Recognizes human DSPP - Epitope Exon 6 (C-terminus of DSP plus DPP domain)
  • Suitable for Immunohistochemistry and Western Blot applications

The two proteins dentin sialoprotein and dentin phosphoprotein are components of dentin, which is a bone-like substance that makes up the protective middle layer of each tooth. Dentin phosphoprotein is thought to be involved in the biomineralization process of dentin. Mutations in this gene have been associated with dentinogenesis imperfecta-1.

From the laboratory of Larry W. Fisher, PhD, National Institute of Dental and Craniofacial Research/NIH.

Catalog Number Product DataSheet Size AVAILABILITY Price Qty
ENH082-FP
Anti-Dentin Sialophosphoprotein (DSPP), human DSP/DPP domains [LF-154] Antibody
100uL In stock
Regular Price:$306.00
On Sale:

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Specifications

Product Type: Antibody
Accession ID: NP_055023.2
Antigen: Dentin Sialophosphoprotein (DSPP), human
Molecular Weight: 131151 Da
Clonality: Polyclonal
Clone Name: LF-154
Reactivity: Human
Immunogen: Recombinant protein (E. coli)
Species Immunized: Rabbit
Epitope: Exon 6 (C-terminus of DSP plus DPP domain)
Buffer: Whole serum
Tested Applications: WB 1:2000, IHC 1:300
Storage: -80C
Shipped: Dry Ice

Provider
From the laboratory of Larry W. Fisher, PhD, National Institute of Dental and Craniofacial Research.
Comments
Note: cleaved DPP domain is not efficiently retained on nitrocellulose or PVDF membranes.
References
  1. Midura RJ, Midura SB, Su X, Gorski JP. Separation of newly formed bone from older compact bone reveals clear compositional differences in bone matrix. Bone. 2011 Dec;49(6):1365-74.
  2. Maciejewska I, Sakowicz-Burkiewicz M, Pawelczyk T. Id1 Expression Level Determines the Differentiation of Human Dental Pulp Stem Cells. J Dent Res. 2014 Jun;93(6):576-81.
  3. Kereshanan S, Stephenson P, Waddington R. Identification of dentine sialoprotein in gingival crevicular fluid during physiological root resorption and orthodontic tooth movement. Eur J Orthod. 2008 Jun;30(3):307-14.

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