Anti-Biglycan (bovine) [LF-96] Antibody
![Anti-Biglycan (bovine) [LF-96] Antibody](https://www.kerafast.com/MediaStorage/Product/Images/Large/1508_2001202001265015070.jpg "Anti-Biglycan (bovine) [LF-96] Antibody")
This rabbit IgG polyclonal antibody was generated against conjugated epitope peptide corresponding to bovine biglycan and recognizes cow, sheep and similar mammals biglycan.
Highlights:
- Recognizes cow, sheep and similar mammals biglycan - Epitope amino acid sequence LPDLDSLPPTYSC
- Suitable for Immunohistochemistry and Western Blot applications
Biglycan is a small leucine-rich repeat proteoglycan (SLRP) which is found in a variety of extracellular matrix tissues, including bone, cartilage and tendon. In humans it is encoded by the BGN gene located on the X chromosome and is mainly involved in collagen fiber assembly.
From the laboratory of Larry W. Fisher, PhD, National Institute of Dental and Craniofacial Research/NIH.
This rabbit IgG polyclonal antibody was generated against conjugated epitope peptide corresponding to bovine biglycan and recognizes cow, sheep and similar mammals biglycan.
Highlights:
- Recognizes cow, sheep and similar mammals biglycan - Epitope amino acid sequence LPDLDSLPPTYSC
- Suitable for Immunohistochemistry and Western Blot applications
Biglycan is a small leucine-rich repeat proteoglycan (SLRP) which is found in a variety of extracellular matrix tissues, including bone, cartilage and tendon. In humans it is encoded by the BGN gene located on the X chromosome and is mainly involved in collagen fiber assembly.
From the laboratory of Larry W. Fisher, PhD, National Institute of Dental and Craniofacial Research/NIH.
This product is for sale to Nonprofit customers only. For profit customers, please Contact Us for more information.
| Product Type: | Antibody |
| Antigen: | Bigylcan, bovine |
| Accession ID: | P21810 |
| Molecular Weight: | 41590 Da |
| Clonality: | Polyclonal |
| Clone Name: | LF-96 |
| Reactivity: | Cow, Sheep & possibly similar mammals by peptide conservation |
| Immunogen: | conjugated epitope peptide |
| Species Immunized: | Rabbit |
| Epitope: | LPDLDSLPPTYSC |
| Buffer: | Whole serum |
| Tested Applications: | WB 1:2000, IHC 1:200 |
| Storage: | -80C |
| Shipped: | Cold Packs (Domestic, Overnight); Dry Ice (International) |
- Fisher LW, Stubbs JT 3rd, Young MF. Antisera and cDNA probes to human and certain animal model bone matrix noncollagenous proteins. Acta Orthop Scand Suppl. 1995 Oct;266:61-5. PubMed PMID: 8553864.
- Kinsella MG, Tsoi CK, Järveläinen HT, Wight TN. Selective expression and processing of biglycan during migration of bovine aortic endothelial cells. The role of endogenous basic fibroblast growth factor. J Biol Chem. 1997 Jan 3;272(1):318-25. PubMed PMID: 8995264.
- Pearson D, Sasse J. Differential regulation of biglycan and decorin by retinoic acid in bovine chondrocytes. J Biol Chem. 1992 Dec 15;267(35):25364-70. PubMed PMID: 1460033.
- Melrose J, Ghosh P, Taylor TK, Vernon-Roberts B, Latham J, Moore R. Elevated synthesis of biglycan and decorin in an ovine annular lesion model of experimental disc degeneration. Eur Spine J. 1997;6(6):376-84. PubMed PMID: 9455664; PubMed Central PMCID: PMC3467725.
- Connelly JT, Wilson CG, Levenston ME. Characterization of proteoglycan production and processing by chondrocytes and BMSCs in tissue engineered constructs. Osteoarthritis Cartilage. 2008 Sep;16(9):1092-100. doi: 10.1016/j.joca.2008.01.004. Epub 2008 Feb 21. PubMed PMID: 18294870; PubMed Central PMCID: PMC2605680.
- Vogel KG, Peters JA. Histochemistry defines a proteoglycan-rich layer in bovine flexor tendon subjected to bending. J Musculoskelet Neuronal Interact. 2005 Mar;5(1):64-9. PubMed PMID: 15788872.
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