Anti-Stargazin-like TARP (CACNG2) Antibody
This rabbit polyclonal antibody was generated against the cytoplasmic domain of stargazin/TARPgamma-2 (CACNG2, stargazin) and recognizes stargazin/g-2 and other TARP family proteins (g-3, g-4 and g-8).
Highlights:
- Reacts with stargazin (CACNG2, TARP gamma-2), gamma-3, gamma-4 and gamma-8
- Suitable for Immunohistochemistry and biochemistry (western blotting and immunoprecipitation) applications
Stargazin (Voltage-dependent calcium channel gamma-2 subunit, CANG2, TARP gamma-2) regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). It promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. It does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. It is thought to stabilize the calcium channel in an inactivated (closed) state.
From the laboratory of Susumo Tomita, PhD, Yale University.
This rabbit polyclonal antibody was generated against the cytoplasmic domain of stargazin/TARPgamma-2 (CACNG2, stargazin) and recognizes stargazin/g-2 and other TARP family proteins (g-3, g-4 and g-8).
Highlights:
- Reacts with stargazin (CACNG2, TARP gamma-2), gamma-3, gamma-4 and gamma-8
- Suitable for Immunohistochemistry and biochemistry (western blotting and immunoprecipitation) applications
Stargazin (Voltage-dependent calcium channel gamma-2 subunit, CANG2, TARP gamma-2) regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). It promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. It does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. It is thought to stabilize the calcium channel in an inactivated (closed) state.
From the laboratory of Susumo Tomita, PhD, Yale University.
| Product Type: | Antibody |
| Antigen: | TARPg-2/Stargazin |
| Accession ID: | Q9Y698 |
| Molecular Weight: | 36 kDa |
| Clonality: | Polyclonal |
| Reactivity: | Human, mouse, rat (others not tested) |
| Immunogen: | The cytoplasmic domain of TARPg-2/stargazin |
| Species Immunized: | Rabbit |
| Purification Method: | Affinity purified on agarose column containing the immunizing antigen |
| Tested Applications: | WB, IP, IHC |
| Storage: | -80C |
| Shipped: | Dry Ice |
- Tomita S, Chen L, Kawasaki Y, Petralia RS, Wenthold RJ, Nicoll RA, Bredt DS. Functional studies and distribution define a family of transmembrane AMPA receptor regulatory proteins. J Cell Biol. 2003 May 26;161(4):805-16.
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