This mouse monoclonal antibody was generated against full-length recombinant cyclin E (CYE-1) protein and is specific for Caenorhabditis elegans CYE-1 full-length recombinant protein (prepared in bacteria).
Cyclin E is a member of the cyclin family of proteins, which regulates the cell cycle through its activation of cyclin-dependent kinases. Specifically, cyclin E binds and activates the S phase Cdk2. The cyclin E–Cdk2 complex promotes the G1 to S phase cell cycle transition. Overexpression of cyclin E has been implicated in carcinomas among the gastrointestinal tract, including colon or stomach cancer as well as a marker for breast cancers.
From the laboratory of Edward T. Kipreos, PhD, University of Georgia.
|Antigen:||C. elegans CYE-1 full-length recombinant protein (prepared in bacteria)|
|Molecular Weight:||60.6 kDa|
|Immunogen:||Full-length recombinant CYE-1 protein|
|Purification Method:||Not purified, available as antibody supernatant|
|Buffer:||Cell culture supernatant|
|Tested Applications:||Immunofluorscence (1:100-300) and Western Blot|
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