Anti-Ferrochelatase (FECH) Antibody
This rabbit polyclonal antibody was generated against ferrochelatase (FECH) and recognizes mammalian, recombinant-source FECH.
Highlights:
- Reacts with mammalian, recombinant-source FECH
- Suitable for Immunoblot and Western Blot applications
Ferrochelatase is an enzyme that is encoded by the FECH gene in humans. Ferrochelatase, the terminal enzyme component of the mitochondrial heme biosynthesis complex essential to the formation of heme in mammals. It converts protoporphyrin IX into heme B.
From the laboratory of Harry A. Dailey, PhD, University of Georgia.
This rabbit polyclonal antibody was generated against ferrochelatase (FECH) and recognizes mammalian, recombinant-source FECH.
Highlights:
- Reacts with mammalian, recombinant-source FECH
- Suitable for Immunoblot and Western Blot applications
Ferrochelatase is an enzyme that is encoded by the FECH gene in humans. Ferrochelatase, the terminal enzyme component of the mitochondrial heme biosynthesis complex essential to the formation of heme in mammals. It converts protoporphyrin IX into heme B.
From the laboratory of Harry A. Dailey, PhD, University of Georgia.
Specifications
| Product Type: | Antibody |
| Alternative Name(s): | FECH |
| Antigen: | Ferrochelatase |
| Accession ID: | P22830 |
| Host: | Rabbit |
| Clonality: | Polyclonal |
| Reactivity: | Mammalian, recombinant-source FeCH |
| Immunogen: | Ferrochelatase (not sure if native or recombinant) |
| Buffer: | Whole serum |
| Tested Applications: | Immunoblot and Western Blot (1:30000 to 50000) |
| Storage: | <1 month at 4C, >1 month at -80C |
| Shipped: | Cold Packs (Domestic, Overnight); Dry Ice (International) |
Provider
From the laboratory of Harry A. Dailey, PhD, University of Georgia.
References
- Medlock AE, Shiferaw MT, Marcero JR, Vashisht AA, Wohlschlegel JA, Phillips JD, Dailey HA. Identification of the Mitochondrial Heme Metabolism Complex. PLoS One. 2015 Aug 19;10(8):e0135896.
- Yien YY, Shi J, Chen C, Cheung JT, Grillo AS, Shrestha R, Li L, Zhang X, Kafina MD, Kingsley PD, King MJ, Ablain J, Li H, Zon L, Palis J, Burke MD, Bauer DE, Orkin SH, Koehler CM, Phillips JD, Kaplan J, Ward DM, Lodish HF, Paw BH. FAM210B is an erythropoietin target and regulates erythroid heme synthesis by controlling mitochondrial iron import and ferrochelatase activity. J Biol Chem. 2018 Oct 26. pii: jbc.RA118.002742. View Article
If you publish research with this product, please let us know so we can cite your paper.
