This rabbit polyclonal antibody was generated against intact recombinant human delta-aminolevulinate synthase 2 (ALAS2) and recognizes mammalian, recombinant-source ALAS2.
Aminolevulinic acid synthase or ALAS is an enzyme that catalzyes the synthesis of D-Aminolevulinic acid (ALA) the first common precursor in the biosynthesis of all tetrapyrroles such as hemes, cobalamins and chlorophylls. There are two types of ALAS, 1 and 2. Type 2 is expressed in red blood cells where as Type 1 is ubiquitously expressed throughout the body. Mutations in ALAS2 have been linked to X-linked sideroblastic anemia where red blood cells appear in the bone marrow.
From the laboratory of Harry A. Dailey, PhD, University of Georgia.
|Product Type:||Small Molecule|
|Antigen:||Aminolevulinate Synthase 2|
|Reactivity:||Mammalian, recombinant-source ALAS2|
|Immunogen:||Intact recombinant human ALAS2|
Recombinant hALAS isoforms overexpressed in E. coli. Primary Ab 1:25k, anti-ALAS2 in 1% BSA. Secondary Ab, 1:50k dylight 650 anti-rabbit in 1% BSA.
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