Anti-Hereditary Hemochromatosis Protein (HFE) Antibody

This rabbit IgG polyclonal antibody was raised against a 16 C-terminal amino acids based on the cDNA of the hereditary hemochromatosis protein (HFE) protein and is specific for human HFE.

Highlights:

  • Recognizes human HFE
  • Suitable for Western Blot, Immunoprecipitation and Immunohistochemistry applications

The HFE protein is a membrane protein that is similar to MHC class I-type proteins and associates with beta-2 microglobulin (beta2M). It is thought that this protein functions to regulate circulating iron uptake by regulating the interaction of the transferrin receptor with transferrin. Mutations in the gene can cause an iron storage disorder called hereditary hemochromatosis (HCC), it results in excessive intestinal absorption of dietary iron resulting in a pathological increase in total body iron stores.

From the laboratory of Abdul Waheed, PhD, St. Louis University.

Catalog Number Product Size AVAILABILITY Price Qty
ESL218
Anti-Hereditary Hemochromatosis Protein (HFE) Antibody
100uL In stock
Regular Price:$306.00
Specifications

Provider
From the laboratory of Abdul Waheed, PhD, St. Louis University.
References
  1. Hannuksela, J., Parkkila, S., Waheed, A., Britton, R. S., Fleming, R. E., Bacon, B. R. and Sly, W. S. (2003), Human platelets express hemochromatosis protein (HFE) and transferrin receptor 2. European Journal of Haematology, 70: 201–206.

If you publish research with this product, please let us know so we can cite your paper.

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