This rabbit IgG polyclonal antibody was raised against a 15-amino acid peptide (e35-F51) of the C-terminal region of Human Transferrin Receptor 2 (TfR2) and is specific for human HTFR2.
The HTFR2 is a glycoprotein that is involved in the uptake of transferrin-bound iron into cells by endocytosis. The transferrin receptor family of proteins are needed to import iron into the cell and is regulated in response to intracellular iron concentration. TfR2 is restricted to certain cell types and is unaffected by intracellular iron concentrations and has a lower affinity than TfR1.
From the laboratory of Abdul Waheed, PhD, St. Louis University.
|Molecular Weight:||87 kDa|
|Immunogen:||15-amino acid peptide (e35-F51) of the C-terminal region of human TfR2|
|Purification Method:||Total Serum|
|Method Used to Determine Concentration:||Purified antibody (anti IgG purification of serum; protein A sepharose resin)|
|Tested Applications:||WB; IP; IH|
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