This mouse IgG1k monoclonal antibody was generated against avian thymic hormone (ATH) paravalbumin and is specific for chicken ATH.
ATH consists of 108 residues (11.7 kDa) thus placing this protein, based on its size, at the intersection between the a and ß lineages (it is a ß-PV). ATH is 82% identical to ß- parvalbumin from Graptemys geographica and is produced primarily in epithelial cells in the thymic cortex and in the eyes of chickens. ATH has been shown to promote maturation in bone marrow cells and is involved in binding to calcium ions.
From the laboratory of William L. Ragland, PhD, University of Georgia.
|Antigen:||Avian Thymic Hormone (β-lineage)|
|Purification Method:||Protein G|
|Buffer:||0.1M Sodium Phosphate, pH 7.4, 0.15M NaCl, 0.05% (w/v) Sodium Azide/td>|
|Tested Applications:||ELISA (1:500), WB, IS, IC-ELISA (1:1000), IF|
Mab 4A6 is specific to ATH and avian thymus extracts and does not cross-react with other parvalbumins or tissue (muscle, liver, etc.) extracts.
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