Anti-Biotin [33] Antibody

This mouse monoclonal antibody was generated against a biotin-keyhole limpet hemocyanin conjugate and recognizes free and haptenic biotin and biocytin.

Highlights:

  • Binds both free and haptenic biotin and biocytin
  • Inhibits biotin-dependent enzymes including Acetly-CoA carboxylase - Useful for assessing the role of biotin in metabolism
  • Useful for biotin-complex labeling techniques where avidin cannot be used

Biotin is composed of a ureido (tetrahydroimidizalone) ring fused with a tetrahydrothiophene ring. A valeric acid substituent is attached to one of the carbon atoms of the tetrahydrothiophene ring. Biotin is a coenzyme for carboxylase enzymes, involved in the synthesis of fatty acids, isoleucine, and valine, and in gluconeogenesis.

From the laboratory of Alec H. Sehon, PhD, University of Manitoba.

Catalog Number Product DataSheet Size AVAILABILITY Price Qty
EMB010
Anti-Biotin [33] Antibody
100ug In stock
Regular Price:$256.00
On Sale:
Specifications

Product Type: Antibody
Antigen: Biotin ( tested for ability to inhibit biotin-dependent enzymes)
Isotype: IgG
Clonality: Monoclonal
Clone Name: UMTT33-M1
Specificity: Biotin
Immunogen: biotin-keyhole limpet hemocyanin conjugate
Species Immunized: female BALB/c mice
Purification Method: Protein G
Buffer: PBS, pH 7.4
Storage: -20C
Shipped: Cold packs

Provider
From the laboratory of Alec H. Sehon, PhD, University of Manitoba.
References
  1. Dakshinamurti K, Bhullar RP, Scoot A, Rector ES, Delespesse G, Sehon AH. Production and characterization of a monoclonal antibody to biotin. Biochem J. 1986 Jul 15;237(2):477-82.

If you publish research with this product, please let us know so we can cite your paper.

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