Anti-Biotin [33] Antibody
![Anti-Biotin [33] Antibody](https://www.kerafast.com/MediaStorage/Product/Images/Large/1255_2001202001264012540.jpg "Anti-Biotin [33] Antibody")
This mouse monoclonal antibody was generated against a biotin-keyhole limpet hemocyanin conjugate and recognizes free and haptenic biotin and biocytin.
Highlights:
- Binds both free and haptenic biotin and biocytin
- Inhibits biotin-dependent enzymes including Acetly-CoA carboxylase - Useful for assessing the role of biotin in metabolism
- Useful for biotin-complex labeling techniques where avidin cannot be used
Biotin is composed of a ureido (tetrahydroimidizalone) ring fused with a tetrahydrothiophene ring. A valeric acid substituent is attached to one of the carbon atoms of the tetrahydrothiophene ring. Biotin is a coenzyme for carboxylase enzymes, involved in the synthesis of fatty acids, isoleucine, and valine, and in gluconeogenesis.
From the laboratory of Alec H. Sehon, PhD, University of Manitoba.
This mouse monoclonal antibody was generated against a biotin-keyhole limpet hemocyanin conjugate and recognizes free and haptenic biotin and biocytin.
Highlights:
- Binds both free and haptenic biotin and biocytin
- Inhibits biotin-dependent enzymes including Acetly-CoA carboxylase - Useful for assessing the role of biotin in metabolism
- Useful for biotin-complex labeling techniques where avidin cannot be used
Biotin is composed of a ureido (tetrahydroimidizalone) ring fused with a tetrahydrothiophene ring. A valeric acid substituent is attached to one of the carbon atoms of the tetrahydrothiophene ring. Biotin is a coenzyme for carboxylase enzymes, involved in the synthesis of fatty acids, isoleucine, and valine, and in gluconeogenesis.
From the laboratory of Alec H. Sehon, PhD, University of Manitoba.
Specifications
| Product Type: | Antibody |
| Antigen: | Biotin ( tested for ability to inhibit biotin-dependent enzymes) |
| Isotype: | IgG |
| Clonality: | Monoclonal |
| Clone Name: | UMTT33-M1 |
| Specificity: | Biotin |
| Immunogen: | biotin-keyhole limpet hemocyanin conjugate |
| Species Immunized: | female BALB/c mice |
| Purification Method: | Protein G |
| Buffer: | PBS, pH 7.4 |
| Storage: | -20C |
| Shipped: | Cold packs |
Provider
From the laboratory of Alec H. Sehon, PhD, University of Manitoba.
References
- Dakshinamurti K, Bhullar RP, Scoot A, Rector ES, Delespesse G, Sehon AH. Production and characterization of a monoclonal antibody to biotin. Biochem J. 1986 Jul 15;237(2):477-82.
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