Anti-Chondroitin Sulfate Proteoglycan 4 (CSPG4) [ME313] Antibody

This mouse IgG1 monoclonal antibody was generated against WM46 melanoma cells and recognizes human chondroitin sulfate proteoglycan 4 (CSPG4).

Highlights:

  • Specific for human CSPG4
  • Suitable for Western Blot applications

Melanoma-associated chondroitin sulfate proteoglycan, encoded by CSPG4 gene, is a surface marker for melanoma, astrocytoma and a variety of head and neck cancers. CSPG4 stabilizes cell-substratum interactions during early events of malignant melanoma cell growth on basal membrane. CSPG4 is an integral membrane chondroitin sulfate proteoglycan protein, 260 kDa of mass, yet may migrate slower on gels depending on glycosylation status.

From the laboratory of Meenhard Herlyn, DVM, DSc, The Wistar Institute.

The Investigator's Annexe Part of The Investigator's Annexe program.

Catalog Number Product DataSheet Size AVAILABILITY Price Qty
EWI022
Anti-Chondroitin Sulfate Proteoglycan 4 (CSPG4) [ME313] Antibody
100ug Currently Unavailable
Regular Price:$321.00
On Sale:
Specifications

Product Type: Antibody
Alternative Name(s): Chondroitin sulfate proteoglycan 4,Chondroitin sulfate proteoglycan NG2,Melanoma chondroitin sulfate proteoglycan,Melanoma-associated chondroitin sulfate proteoglycan
Accession ID: HGNC: 2466 OMIM: 601172 UniProtKB: Q6UVK1 Entrez Gene: 1464 Ensembl: ENSG00000173546
Antigen: Melanoma-associated chondroitin sulfate proteoglycan; chondroitin sulfate proteoglycan, CSPG4
Molecular Weight: 260+ kDa
Isotype: IgG1
Clonality: Monoclonal
Clone Name: ME31.3 or ME313
Reactivity: Human
Immunogen: WM46 melanoma cells
Species Immunized: Mouse
Purification Method: Protein G
Buffer: 0.1M Sodium Phosphate, pH 7.4, 0.15M NaCl, 0.05% (w/v) Sodium Azide
Tested Applications: WB (1:1000)
Storage: -20C
Shipped: Cold packs

Provider
From the laboratory of Meenhard Herlyn, DVM, DSc, The Wistar Institute.
References
  1. Folberg R, Donoso LA, Atkinson BF, Ernst CS, Herlyn M, Arbizo VV. An antimelanoma monoclonal antibody and the histopathology of uveal melanomas. Arch Ophthalmol. 1985 Feb;103(2):275-9. PubMed PMID: 2579631.

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