This mouse IgG monoclonal antibody was generated against carcinoma cells and recognizes human Tetraspanin-8 (Tspan8).
CO-029/TSPAN8 is a glycoprotein and a member of transmembrane 4 superfamily, also known as the tetraspanin family. CO-029/TSPAN8 is a cell-surface protein that is characterized by the presence of four hydrophobic domains. CO-029/TSPAN8 controls signaling regulation of cell development, activation, growth and motility. CO-029/TSPAN8 also forms a complex with integrins and is expressed in various carcinomas.
From the laboratory of Meenhard Herlyn, DVM, DSc, The Wistar Institute.
Part of The Investigator's Annexe program.
|Alternative Name(s):||Tetraspanin-8, Tspan-8,Transmembrane 4 superfamily member 3 Tumor-associated antigen CO-029|
|Antigen:||CO-029 or TSPAN8|
|Accession ID:||UniProtKB: P19075 HGNC: 11855 Entrez Gene: 7103 OMIM: 600769 Ensembl: ENSG00000127324|
|Molecular Weight:||27-34 kDa|
|Epitope:||CO-029 recognizes TSPAN8, a cell surface glycoprotein|
|Purification Method:||Protein G|
|Buffer:||0.1M Sodium Phosphate, pH 7.4, 0.15M NaCl, 0.05% (w/v) Sodium Azide|
|Tested Applications:||WB (1:1000), IF (1:50)|
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