Anti-Tetraspanin-8 (Tspan8) [CO-029] Antibody

This mouse IgG monoclonal antibody was generated against carcinoma cells and recognizes human Tetraspanin-8 (Tspan8).

Highlights:

  • Specific for human Tspan8
  • Suitable for Western Blot and Immunofluorescence applications

CO-029/TSPAN8 is a glycoprotein and a member of transmembrane 4 superfamily, also known as the tetraspanin family. CO-029/TSPAN8 is a cell-surface protein that is characterized by the presence of four hydrophobic domains. CO-029/TSPAN8 controls signaling regulation of cell development, activation, growth and motility. CO-029/TSPAN8 also forms a complex with integrins and is expressed in various carcinomas.

From the laboratory of Meenhard Herlyn, DVM, DSc, The Wistar Institute.

The Investigator's Annexe Part of The Investigator's Annexe program.

Catalog Number Product DataSheet Size AVAILABILITY Price Qty
EWI019
Anti-Tetraspanin-8 (Tspan8) [CO-029] Antibody
100ug In Stock
Regular Price:$321.00
On Sale:
Specifications

Product Type: Antibody
Alternative Name(s): Tetraspanin-8, Tspan-8,Transmembrane 4 superfamily member 3 Tumor-associated antigen CO-029
Antigen: CO-029 or TSPAN8
Accession ID: UniProtKB: P19075 HGNC: 11855 Entrez Gene: 7103 OMIM: 600769 Ensembl: ENSG00000127324
Molecular Weight: 27-34 kDa
Isotype: IgG
Clonality: Monoclonal
Clone Name: CO-029
Reactivity: Human
Immunogen: Carcinoma cells
Species Immunized: Mouse
Epitope: CO-029 recognizes TSPAN8, a cell surface glycoprotein
Purification Method: Protein G
Buffer: 0.1M Sodium Phosphate, pH 7.4, 0.15M NaCl, 0.05% (w/v) Sodium Azide
Tested Applications: WB (1:1000), IF (1:50)
Concentration: 1.93mg/mL
Storage: -20C
Shipped: Cold packs

Provider
From the laboratory of Meenhard Herlyn, DVM, DSc, The Wistar Institute.
References
  1. Koprowski H, Steplewski Z, Mitchell K, Herlyn M, Herlyn D, Fuhrer P. Colorectal carcinoma antigens detected by hybridoma antibodies. Somatic Cell Genet. 1979 Nov;5(6):957-71.
  2. Szala S, Kasai Y, Steplewski Z, Rodeck U, Koprowski H, Linnenbach AJ. Molecular cloning of cDNA for the human tumor-associated antigen CO-029 and identification of related transmembrane antigens. Proc Natl Acad Sci U S A. 1990 Sep;87(17):6833-7.

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