The MC-38 MUC-1 Cell Line was derived from a murine colon adenocarcinoma and is engineered to express human Mucin 1, cell surface associated (MUC-1).
MUC1 or polymorphic epithelian mucin (PEM) is a part of the mucin family, which are glycosylated proteins produced by epithelian tissues. Mucins are O-glycosylated proteins that play an essential role in forming protective mucous barriers on epithelial surfaces. These proteins also play a role in intracellular signaling. This protein is expressed on the apical surface of epithelial cells that line the mucosal surfaces of many different tissues including lung, breast stomach and pancreas.
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|Product Type:||Cell Line|
|Growth Conditions:||DMEM with 10 % FBS, 2mM glutamine, 0.1mM nonessential amino acids and 1mM sodium pyruvate and 50ug/ml gentamycin sulfate, 300 ug/ml G418|
|Subculturing:||1:5, or 1:10|
|Cryopreservation:||90% FBS + 10% DMSO|
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