This mouse IgG monoclonal antibody was generated against recombinant LIM domain-containing protein 2 (LIMD2) protein and recognizes the N-terminus of human LIMD2.
LIMD2, is a protein overexpressed in metastatic lesions at higher levels by comparison to the matched primary tumor tissue. LIMD2 drives motility and invasion through binding directly to the kinase domain of integrin-linked kinase (ILK) and activating ILK signaling pathway. LIMD2 contains a classic LIM-domain structure.
From the laboratory of Frank J. Rauscher, III, PhD, The Wistar Institute.
Part of The Investigator's Annexe program.
|Molecular Weight:||14 kDa|
|Epitope:||N-terminus amino acids 1-127 of human LIMD2|
|Purification Method:||Affinity purified|
|Tested Applications:||WB, IF, IHC|
|Storage:||-20C, avoid freeze thaw cycles|
If you publish research with this product, please let us know so we can cite your paper.