Anti-CD20, C-Terminal [GST77] Antibody

This rabbit polyclonal antibody [GST77] was generated against a recombinant protein comprising C-terminal residues 282-297 of human CD20 linked to GST, and is specific for human CD20 (C-terminus).


  • Reacts with C-terminal residues 282-297 of human CD20
  • Valuable for both pre-clinical and clinical research applications
  • Suitable for Western Blot and Immunoprecipitationapplications

CD20, or B-lymphocyte antigen CD20, is a cell-surface protein expressed in most immune cells arising from the B-cell lineage and plays a role in cellular activation and proliferation. Importantly, CD20 is a recognized biomarker for a number of human disorders, including several autoimmune diseases and B-cell malignancies.

From the laboratory of Julie P. Deans, PhD, University of Calgary.

The Investigator's Annexe Part of The Investigator's Annexe program.

Catalog Number Product Size AVAILABILITY Price Qty
Anti-CD20, C-Terminal [GST77] Antibody
100uL In stock
Regular Price:$299.00

Product Type: Antibody
Antigen: CD20
Molecular Weight: 33-35 kDa
Clonality: Polyclonal
Clone Name: GST77
Reactivity: Human
Immunogen: Peptide fused to GST
Species Immunized: Rabbit
Epitope: C-terminal residues 282-297
Buffer: Serum
Tested Applications: WB (1:5,000), IP
Storage: -80C
Shipped: Dry ice

From the laboratory of Julie P. Deans, PhD, University of Calgary.
  1. Polyak MJ, Tailor SH, Deans JP. Identification of a cytoplasmic region of CD20 required for its redistribution to a detergent-insoluble membrane compartment. J Immunol. 1998 Oct 1;161(7):3242-8.
  2. Deans JP, Robbins SM, Polyak MJ, Savage JA. Rapid redistribution of CD20 to a low density detergent-insoluble membrane compartment. J Biol Chem. 1998 Jan 2;273(1):344-8.
  3. Popoff IJ, Savage JA, Blake J, Johnson P, Deans JP. The association between CD20 and Src-family Tyrosine kinases requires an additional factor. Mol Immunol. 1998 Mar;35(4):207-14.
  4. Polyak MJ, Deans JP. Alanine-170 and proline-172 are critical determinants for extracellular CD20 epitopes; heterogeneity in the fine specificity of CD20 monoclonal antibodies is defined by additional requirements imposed by both amino acid sequence and quaternary structure. Blood. 2002 May 1;99(9):3256-62.
  5. Polyak MJ, Li H, Shariat N, Deans JP. CD20 homo-oligomers physically associate with the B cell antigen receptor. Dissociation upon receptor engagement and recruitment of phosphoproteins and calmodulin-binding proteins. J Biol Chem. 2008 Jul 4;283(27):18545-52.
  6. Sarro SM, Unruh TL, Zuccolo J, Sanyal R, Luider JM, Auer-Grzesiak IA, Mansoor A, Deans JP. Quantification of CD20 mRNA and protein levels in chronic lymphocytic leukemia suggests a post-transcriptional defect. Leuk Res. 2010 Dec;34(12):1670-3.

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