Anti-MS4A4A [3F2] Antibody

This mouse IgG1 monoclonal antibody [3F2] was generated against mouse cell line 300-19 expressing transfected human membrane-spanning 4-domains subfamily A member 4A (MS4A4A)-GFP and is specific for human extracellular MS4A4A.

Highlights:

  • Reacts with human MS4A4A
  • Suitable for FACS and Immunoprecipitation applications

Recombinant versions available at our sister company, Absolute Antibody:

MS4A (membrane-spanning 4-domain family, subfamily A) is a large family of proteins that includes at least 26 members in mouse and humans. Flanked by amino- and carboxyl- cytoplasmic regions, MS4A family members contain four highly conserved transmembrane domains connected by short extracellular and cytoplasmic loops. CD20, the most well-known MS4A family member, is a B-cell-specific molecule associated with the B cell antigen receptor and functions in receptor-activated calcium influx. Several other MS4A family members are likely to be components of oligomeric cell surface complexes involved in signal transduction in diverse cell lineages.

From the laboratory of Julie P. Deans, PhD, University of Calgary.

 

Catalog Number Product DataSheet Size AVAILABILITY Price Qty
EUC002
Anti-MS4A4A [3F2] Antibody
100ug In stock
Regular Price:$299.00
On Sale:
Specifications

Product Type: Antibody
Antigen: MS4A4A
Molecular Weight: 26 kDa
Isotype: IgG1
Clonality: Monoclonal
Clone Name: 3F2
Reactivity: Human
Immunogen: Mouse cell line 300-19 expressing transfected human MS4A4A-GFP
Species Immunized: Mouse
Epitope: Extracellular (same as 4H2)
Purification Method: Protein G Affinity
Buffer: 0.1M Sodium Phosphate, pH 7.4, 0.15M NaCl, 0.05% (w/v) Sodium Azide
Tested Applications: FACS (0.5 ug/106cells), IP (2ug)
Storage: -20C
Shipped: Cold packs

Provider
From the laboratory of Julie P. Deans, PhD, University of Calgary.
Comments

Works best for FACS on primary cells using direct staining.

References
  1. Sanyal R, Polyak MJ, Zuccolo J, Puri M, Deng L, Roberts L, Zuba A, Storek J, Luider JM, Sundberg EM, Mansoor A, Baigorri E, Chu MP, Belch AR, Pilarski LM, Deans JP. MS4A4A: a novel cell surface marker for M2 macrophages and plasma cells. Immunol Cell Biol. 2017 Apr 11. doi: 10.1038/icb.2017.18.

If you publish research with this product, please let us know so we can cite your paper.

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