This rabbit IgG polyclonal antibody was raised against a recombinant mouse proline-rich transmembrane protein 2 (Prrt2)-GST fusion, and recognizes N-terminal human, mouse, and rat PRRT2.
The function of the PRRT protein is unknown, although it is thought to be involved in signaling in the brain. Studies show that it interacts with another protein called SNAP25, which is involved in signaling between nerve cells (neurons) in the brain. SNAP25 helps control the release of neurotransmitters, which are chemicals that relay signals from one neuron to another. Mutations in this protein have been linked to episodic kinesigenic dyskinesia-1, a neurological disorder.
From the laboratory of Abraham L. Brass, MD, PhD, University of Massachusetts Medical School.
Part of The Investigator's Annexe program.
|Antigen:||Prrt2 (mouse), PRRT2 (human)|
|Molecular Weight:||75 kDa|
|Reactivity:||Human, mouse, rat|
|Immunogen:||Recombinant mouse Prrt2-GST fusion|
|Tested Applications:||WB (1:2000), IF (1:2000), IHC (1:1000), IP (1:25)|
|Storage:||-80C long term, thaws can be stored at 4C for 2-3 months|
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