Franklin D. West, PhD, University of Georgia

Franklin D. West, PhD
Franklin D. West, PhD

The West laboratory studies aberrant germ cell development. The lab has developed novel technologies enabling systematic study of gametogenesis in humans and livestock including 1) A robust in vitro pluripotent stem cell to germ cell differentiation culture system capable of generating large numbers of germ like-cells and 2) the development of the only known chimera competent porcine induced pluripotent stem cell line. Utilizing stem cells and advanced molecular and genetic tools, we can address our long term goal of identifying and understand germ cell regulatory signaling in humans and domestic livestock species that could provide invaluable insight into the mechanistic causes of abnormal gametogenesis. Studying important germ cell signaling in human and livestock stem cell derived germ cells may one day lead to the discovery of new targets for drug and toxicology screens, a better understanding of the etiology of diseases caused by errors in germ cell differentiation or even assisted reproductive technologies in domestic livestock species.



  1. Lu Y, West FD, Jordan BJ, Mumaw JL, Jordan ET, Gallegos-Cardenas A, Beckstead RB, Stice SL. Avian-induced pluripotent stem cells derived using human reprogramming factors. Stem Cells Dev. 2012 Feb 10;21(3):394-403.
  2. Shittu I, Zhu Z, Lu Y, Hutcheson JM, Stice SL, West FD, Donadeu M, Dungu B, Fadly AM, Zavala G, Ferguson-Noel N, Afonso CL. Development, characterization and optimization of a new suspension chicken-induced pluripotent cell line for the production of Newcastle disease vaccine. Biologicals. 2016 Jan;44(1):24-32.