Zhi-Ming Zheng, MD, PhD, National Cancer Institute/NIH
Zhi-Ming Zheng, MD, PhD
The Zheng laboratory first identified RNA cis-elements in regulation of alternative RNA splicing in papillomavirus in 1996 and has been studying protein-RNA interactions and their consequences in various infections with tumorviruses, including high-risk human papillomaviruses and Kaposi sarcoma-associated herpesvirus. Their studies aim to understand how RNA splicing and small regulatory RNAs regulate the expression of viral and host genes in viral carcinogenesis. The long-term goal is to develop a series of therapeutic approaches to control viral or cellular gene expression for cancer treatment and to identify biomarkers for clinical diagnosis and prognosis.
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References
- Jia R, Li C, McCoy JP, Deng CX, Zheng ZM. SRp20 is a proto-oncogene critical for cell proliferation and tumor induction and maintenance. Int J Biol Sci. 2010 Dec 15;6(7):806-26. PubMed PMID: 21179588; PubMed Central PMCID: PMC3005347.
