Dawen Cai, PhD, University of Michigan

Dawen Cai, PhD
Dawen Cai, PhD

The Cai Laboratory develops and uses interdisciplinary techniques to study the development and fine tuning of neural circuits in the mouse brain.? Three research areas they are interested in are connectome (a comprehensive map of neural connections in the brain), novel labeling reagents to allow unambiguous identification of a large number of neural lineages and Optical and computational tools using advanced imaging techniques, including multi-color two-photon microscopy to obtain connectome data from intact mouse brain.

The Investigator's Annexe Part of The Investigator's Annexe program.



  1. Cai D, Cohen KB, Luo T, Lichtman JW, Sanes JR. Improved tools for the Brainbow toolbox. Nat Methods. 2013 May 5;10(6):540-7.
  2. Tillberg PW, Chen F, Piatkevich KD, Zhao Y, Yu CJ, English BP, Gao L, Martorell A, Suk HJ, Yoshida F, DeGennaro EM, Roossien DH, Gong G, Seneviratne U, Tannenbaum SR, Desimone R, Cai D, Boyden ES. Protein-retention expansion microscopy of cells and tissues labeled using standard fluorescent proteins and antibodies. Nat Biotechnol 2016;34(9):987-992
  3. Chang JB, Chen F, Yoon YG, Jung EE, Babcock H, Kang JS, Asano S, Suk HJ, Pak N, Tillberg PW, Wassie AT, Cai D, Boyden ES. Iterative expansion microscopy. Nat Methods. 2017 Apr 17. doi: 10.1038/nmeth.4261. [Epub ahead of print] PubMed PMID: 28417997. View Article