Bioconjugation Reagents from Click Chemistry Tools

The term “click chemistry” was coined to describe a class of efficient and selective reactions that can be used to join molecules together rapidly and in high yield. This class of chemical reactions uses bio-orthogonal or biologically unique moieties to label and join two molecules of interest in a two-step procedure.

By labelling a biological moiety with a fluorescent dye, one can track the progress of the biomolecule within a particular environment and also observe interactions with other entities using an array offluorescent technologies.

  Chemoselective Ligation via Copper-free Click Chemistry

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Product Type
Kit 
(5)
Small Molecule 
(308)
Name
Alkyne-Carboxyrhodamine 110 
(2)
Alkyne-PEG4-Acid 
(2)
Alkyne-PEG4-Amine 
(2)
Alkyne-PEG4-Biotin Conjugate 
(1)
Alkyne-PEG4-Maleimide 
(2)
Alkyne-PEG4-NHS Ester 
(2)
Alkyne-TAMRA 
(1)
Azide-Carboxyrhodamine 110 
(2)
Azide-PEG3-Maleimide kit 
(2)
Azide-PEG4-Acid 
(2)
Azide-PEG4-Amine 
(2)
Azide-PEG4-NHS Ester 
(2)
Azide-TAMRA 
(1)
Azidoacetic Acid NHS Ester 
(2)
Azido-Propylamine (3-Azido-1-propanamine) 
(2)
Biotin-PEG3-Azide 
(2)
Cy3 - Alkyne 
(2)
Cy3 - Azide 
(2)
Cy3-Tetrazine 
(2)
Cy5 - Alkyne 
(2)
Cy5 - Azide 
(2)
Cy5-TCO 
(3)
Cy5-Tetrazine 
(2)
Cy7 Alkyne 
(4)
DBCO-Acid 
(2)
DBCO-Amine 
(3)
DBCO-C6-NHS Ester 
(2)
DBCO-Diazo Biotin 
(1)
DBCO-Maleimide 
(3)
DBCO-NHS ester 
(3)
DBCO-PEG 10 kDa 
(2)
DBCO-PEG 20 kDa 
(2)
DBCO-PEG 30 kDa 
(2)
DBCO-PEG 5 kDa 
(2)
DBCO-PEG4-Alcohol 
(3)
DBCO-PEG4-amine 
(2)
DBCO-PEG4-biotin conjugate 
(2)
DBCO-PEG4-DBCO 
(1)
DBCO-PEG4-Desthiobiotin 
(2)
DBCO-PEG4-Maleimide 
(4)
DBCO-PEG4-NHS ester 
(4)
DBCO-PEG4-TAMRA 
(3)
DBCO-PEG5-Acid 
(3)
DBCO-PEG5-NHS Ester 
(5)
Desthiobiotin-PEG3-Azide 
(2)
Desthiobiotin-PEG4-Alkyne 
(2)
Diazo Biotin-Alkyne 
(1)
Diazo Biotin-Azide 
(1)
Methyltetrazine-PEG4-Alkyne 
(3)
Methyltetrazine-PEG4-Azide 
(3)
Methyltetrazine-PEG4-Maleimide 
(3)
Propargyl-Maleimide (1-(Prop-2-yn-1-yl)-1H-pyrrole-2,5-dione ) 
(2)
Propargyl-NHS ester 
(2)
TAMRA-Azide-Biotin 
(2)
TAMRA-Azide-Desthiobiotin 
(2)
TBPTA (Tris[(1-benzyl-1H-1,2,3triazol-4-yl)methyl]amine) 
(3)
Tetrazine?DBCO 
(3)
Tetrazine?PEG5?NHS Ester 
(3)
Tetrazine-PEG5-NHS Ester 
(1)
THPTA (Tris(3-hydroxypropyltriazolylmethyl)amine) 
(3)
Trans-Cyclooctene (TCO)-Amine, HCl Salt 
(3)
Trans-Cyclooctene (TCO)-NHS Ester 
(3)
Trans-Cyclooctene (TCO)-PEG3-Maleimide 
(4)
Trans-Cyclooctene (TCO)-PEG4-NHS Ester 
(4)
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CAS number
1092689-33-2 
(4)
1160761-43-2 
(5)
1345955-28-3 
(4)
124243-00-1 
(2)
1361993-37-4 
(3)
1380500-88-8 
(4)
1380500-92-4 
(4)
1400191-52-7 
(4)
1644644-96-1 
(4)
1658458-26-4 
(3)
1431618-70-0 
(4)
1682653-80-0 
(4)
361154-30-5 
(3)
61135-33-9 
(7)
653600-56-7 
(3)
82909-47-5 
(3)
88192-19-2 
(2)
935658-93-8 
(3)
942518-29-8 
(3)
98891-36-2 
(3)
899452-51-8 
(2)
98924-81-3 
(3)
N/A 
(61)
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Solubility
DCM, Chloroform, DMSO, DMF 
(17)
DMF, DMSO, DCM, THF 
(19)
DMSO, DMF 
(39)
DMSO, DMF, DCM, Chloroform, THF 
(17)
DMSO, DMF, DCM, EtOAc 
(2)
DMSO, DMF, DCM, MeOH 
(6)
DMSO, DMF, DCM, THF 
(3)
DMSO, DMF, DCM, THF, CHCl3 
(8)
DMSO, DMF, DCM, THF, Chloroform 
(38)
DMSO, DMF, MeOH 
(9)
DMSO, DMF, MeOH, DCM, THF 
(9)
DMSO, DMF, MeOH, Water 
(1)
DMSO, DMF, THF 
(4)
DMSO, DMF, THF, DCM 
(2)
DMSO, DMF, THF, DCM, Chloroform 
(3)
DMSO, DMF, THF, MeOH 
(4)
DMSO, DMF, Water 
(6)
DMSO, DMF, water, MeOH 
(4)
Water, DMSO, DMF 
(26)
Water, DMSO, DMF, DCM 
(8)
Water, DMSO, DMF, DCM, Chloroform 
(6)
Water, DMSO, DMF, MeOH 
(60)
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Enrichment Target
Alkyne- or azide-tagged proteins 
(1)
Alkyne-modified proteins 
(2)
Alkyne-tagged proteins 
(2)
Azide-modified proteins 
(5)
Azide-tagged proteins 
(1)
Molecular Weight Left Behind
100.07 
(3)
100.7 
(1)
188.25 
(1)
55.07 
(2)
Bead Size
Spherical, 50-150um 
(5)
Coating
Highly crosslinked, proprietary (non-styrene) polymer matrix 
(3)
Mean Bead Diameter
0.8-1um 
(1)
0.97um 
(2)
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