Recombinant SARS-CoV-2 (2019-nCoV) Spike S1 Protein, expresssed in HEK cells.
The spike (S) glycoprotein of coronaviruses contains protrusions that will only bind to certain receptors on the host cell. Known receptors that bind S1 are ACE2, DPP4, APN, etc. The spike protein is essential for both host specificity and viral infectivity. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.
|Name:||SARS COV-2 Spike S1|
|Alternative Name(s):||Spike protein; COVID19; COVID 19; S protein; SARS-CoV S protein; S glycoprotein; E2; Peplomer protein; Spike protein S1; SARS Coronavirus; SARS-CoV-2; SARS CoV 2; 2019- nCoV|
|Source:||Expressed recombinantly in HEK Cells|
|Molecular Weight:||The recombinant SARS-CoV-2 (2019-nCoV) Spike Protein (S1 Subunit, His Tag) consists of 681 amino acids and predicts a molecular mass of 76.5 kDa.|
|Amino Acid Sequence:||Amino acids: V16-R685|
|Fusion Tag(s):||His tagged|
|Purity:||>90 % by SDS-PAGE|
|Comments:||Manufactured in an ISO 9001:20015 Certified Laboratory|
|Storage:||Store at -20 degree C, for extended storage|
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