Mouse TRb Antibodies
![Anti-Mouse TRb [#6036] Antibody](https://www.kerafast.com/MediaStorage/Product/Images/Large/1046_2001202001263210450.jpg "Anti-Mouse TRb [#6036] Antibody")
These rabbit IgG polyclonal antibodies were raised against full-length mouse thyroid hormone receptor beta (TRb) expressed E. coli and recognize mouse TRb.
Highlights:
- Reacts with mouse TRb
- Suitable for ChIP assay applications
The thyroid hormone receptor (TR) is a type of nuclear receptor that is activated by binding thyroid hormone. TRs act as transcription factors, ultimately affecting the regulation of gene transcription and translation. Mutations in the TRb are known to be a cause of generalized thyroid hormone resistance (GTHR), a syndrome characterized by goiter and high levels of circulating thyroid hormone (T3-T4), with normal or slightly elevated thyroid stimulating hormone (TSH).
From the laboratory of Robert J. Denver, PhD, University of Michigan.
These rabbit IgG polyclonal antibodies were raised against full-length mouse thyroid hormone receptor beta (TRb) expressed E. coli and recognize mouse TRb.
Highlights:
- Reacts with mouse TRb
- Suitable for ChIP assay applications
The thyroid hormone receptor (TR) is a type of nuclear receptor that is activated by binding thyroid hormone. TRs act as transcription factors, ultimately affecting the regulation of gene transcription and translation. Mutations in the TRb are known to be a cause of generalized thyroid hormone resistance (GTHR), a syndrome characterized by goiter and high levels of circulating thyroid hormone (T3-T4), with normal or slightly elevated thyroid stimulating hormone (TSH).
From the laboratory of Robert J. Denver, PhD, University of Michigan.
| Catalog Number | Product | DataSheet | Size | AVAILABILITY | Price | Qty |
|---|
| Product Type: | Antibody |
| Antigen: | Mouse thyroid hormone receptor beta (TRb) |
| Accession ID: | P37242 |
| Isotype: | IgG |
| Clonality: | Polyclonal |
| Clone Name: | 6036 or 6037 |
| Reactivity: | Mouse, other mammals, possibly other vertebrates |
| Immunogen: | Full-length mouse TRbeta expressed in E. coli |
| Species Immunized: | Rabbit |
| Buffer: | Serum |
| Tested Applications: | ChIP assay |
| Storage: | -80C |
| Shipped: | Cold Packs (Domestic, Overnight); Dry Ice (International) |
- Bagamasbad, P., Bonett, R.M., Sachs, L., Buisine, N., Raj, S., Knoedler, J.R., Kyono, Y., Ruan, Y., Ruan, X. and Denver, R.J. (2015) Deciphering the regulatory logic of an ancient, ultraconserved nuclear receptor enhancer module. Molecular Endocrinology 29:856-872 doi: 10.1210/me.2014-1349 PMID:25866873.
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