Xenopus CRF Antibodies

These rabbit IgG polyclonal antibodies were raised against human alpha globulins corticotropin releasing factor (xCRF) conjugate and recognize xenopus CRF.

Highlights:

  • Reacts with xenopus CRF
  • Suitable for Radioimmunoassay and Immunohistochemistry applications

Corticotropin-releasing hormone (CRH) (also known as corticotropin-releasing factor (CRF) or corticoliberin; is a peptide hormone involved in the stress response. It is a releasing hormone that belongs to corticotropin-releasing factor family. Its main function is the stimulation of the pituitary synthesis of ACTH, as part of the HPA Axis. Increased CRH production has been observed to be associated with Alzheimer's disease and major depression.

From the laboratory of Robert J. Denver, PhD, University of Michigan.

Catalog Number Product DataSheet Size AVAILABILITY Price Qty
EMU012
Anti-Xenopus CRF [#1104] Antibody
100uL In stock
Regular Price:$310.00
On Sale:
EMU011
Anti-Xenopus CRF [#1102] Antibody
100uL 1-2 weeks
Regular Price:$310.00
On Sale:
Specifications

Product Type: Antibody
Antigen: Xenopus corticotropin releasing factor (xCRF)
Accession ID: P06850
Molecular Weight: 4758 Da
Isotype: IgG
Clonality: Polyclonal
Clone Name: 1102 or 1104
Reactivity: Anuran amphibians
Immunogen: Human alpha globulins-xCRF conjugate
Species Immunized: Rabbit
Buffer: Serum
Tested Applications: Radioimmunoassay (1:10K-1:50K); immunohistochemistry 
Comments: Antiserum #1104 has the highest titer
Storage: -80C
Shipped: Cold Packs (Domestic, Overnight); Dry Ice (International)

Provider
From the laboratory of Robert J. Denver, PhD, University of Michigan.
References
  1. Denver, R.J. (1997) Environmental stress as a developmental cue: Corticotropin-releasing hormone is a proximate mediator of adaptive phenotypic plasticity in amphibian metamorphosis. Hormones and Behavior 31:169-179.
  2. Boorse, G.C. and Denver, R.J. (2004) Expression and hypophysiotropic actions of corticotropin releasing factor in Xenopus laevis. General and Comparative Endocrinology 137:272-282.
  3. Yao, M., Westphal, N. and Denver, R.J. (2004) Neuroanatomical distribution and stressor-induced activation of central corticotropin-releasing factor neurons in Xenopus laevis. Journal of Neuroendocrinology 16:880-893.
  4. Yao,M., Stenzel-Poore, M. and Denver, R.J. (2007) Structural and functional conservation of vertebrate corticotropin-releasing factor genes: evidence for a critical role for a conserved cyclic AMP response element. Endocrinology 148:2518-2531.

If you publish research with this product, please let us know so we can cite your paper.

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