These mouse monoclonal antibodies were raised against recombinant chicken interleukin 17A (IL-17A) and recognize chicken IL-17A.
Interleukin 17A is proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). Elevated levels of IL17A are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.
From a laboratory at United States Department of Agriculture/USDA.
|Molecular Weight:||57 kDa|
Clone IG8: IgG1
Clone 2A2: IgG2b
|Purification Method:||Protein G|
|Buffer:||PBS, 0.05% (w/v) Sodium Azide|
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