These mouse monoclonal antibodies were raised against purified yeast chicken interleukin 10 (IL-10) and recognize chicken IL-10.
IL-10 also known as human cytokine synthesis inhibitory factor (CSIF) is a cytokine with multiple effects in immunoregulation and inflammation. It downregulates the expression of Th1 cytokines, MHC class II antigens, and co-stimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. IL-10 can block NF-kB activity, and is involved in the regulation of the JAK-STAT signaling pathway.
From a laboratory at United States Department of Agriculture/USDA.
|Accession ID:||P22301, NM_001004414.2|
Clone 11F9: 18.3 kDa
Clone 13B11: I8.3 kDa
Other clones unknown
|Immunogen:||Purified yeast chIL-10|
|Purification Method:||Protein G|
|Buffer:||PBS, 0.05% (w/v) Sodium Azide|
|Tested Applications:||WB (1:1000), ELISA|
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