Anti-CPG2 Antibodies
These mouse monoclonal antibodies were raised against peptide and recognize mouse and rat candidate plasticity protein 2b (CPG2).
Highlights:
- Recognizes mouse and rat CPG2
- Specific to the clathrin-coated pits
in the postsynaptic zone in glutamatergic synapses
- Unique specificity enables high-resolution imaging of
glutamatergic synapses, in contrast to antibodies to other
proteins such as PSD-95 that are expressed in other
synaptic sites
- Suitable for Western Blot, Immunohistochemistry, and Immunoprecipitation applications
Candidate plasticity protein 2 (CPG2) is a protein that is regulated by neuronal activity in the rodent brain. CPG2 is uniquely expressed in the postsynaptic zones of glutamatergic (excitatory) synapses, so antibodies to CPG2 would be an excellent tool for studying excitatory synaptic activity in mice and rats.
From the laboratory of Elly Nedivi, PhD, Massachusetts Institute of Technology.
These mouse monoclonal antibodies were raised against peptide and recognize mouse and rat candidate plasticity protein 2b (CPG2).
Highlights:
- Recognizes mouse and rat CPG2
- Specific to the clathrin-coated pits in the postsynaptic zone in glutamatergic synapses
- Unique specificity enables high-resolution imaging of glutamatergic synapses, in contrast to antibodies to other proteins such as PSD-95 that are expressed in other synaptic sites
- Suitable for Western Blot, Immunohistochemistry, and Immunoprecipitation applications
Candidate plasticity protein 2 (CPG2) is a protein that is regulated by neuronal activity in the rodent brain. CPG2 is uniquely expressed in the postsynaptic zones of glutamatergic (excitatory) synapses, so antibodies to CPG2 would be an excellent tool for studying excitatory synaptic activity in mice and rats.
From the laboratory of Elly Nedivi, PhD, Massachusetts Institute of Technology.
| Catalog Number | Product | DataSheet | Size | AVAILABILITY | Price | Qty |
|---|
| Product Type: | Antibody |
| Name: | Candidate plasticity protein 2 (CPG2) Antibodies |
| Antigen: | CPG2 |
| Accession ID: | Q6PLD8 |
| Isotype: | IgG2a (200A5, 200A9); IgG1 (200A6) |
| Clonality: | Monoclonal |
| Clone Name: | 200A5, 200A6, 200A9 |
| Reactivity: | Mouse, Rat |
| Immunogen: | Peptide (RKLESTLTGLEQSRERQERR) |
| Species Immunized: | Mouse |
| Purification Method: | Protein G |
| Buffer: | PBS, 0.05% (w/v) Sodium Azide |
| Tested Applications: | WB, IHC, IP |
| Storage: | -20C |
| Shipped: | Cold packs |
CPG2 Stain Of Postsynaptic Glutamatergic Synapses
Individual spines from cultured neurons stained for actin filaments (green), CPG2 (red), and PSD-95 (blue). Scale bar, 1 um.
Adapted from: Cottrell JR et al., Neuron. 2004 Nov 18;44(4):677-90.- Cottrell JR, Borok E, Horvath TL, Nedivi E. CPG2: a brain- and synapse-specific protein that regulates the endocytosis of glutamate receptors. Neuron. 2004 Nov 18;44(4):677-90. PubMed PMID: 15541315; PubMed Central PMCID: PMC3065105.
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