Cy5.5 hydrazide

Cyanine5.5 hydrazide is a carbonyl-reactive near infrared dye.

Hydrazides quickly react with carbonyl compounds, such as aldehydes and ketones, and form stable hydrazones. This reaction is useful for the preparation of labeled conjugates. Carbonyl groups in biomolecules can form spontaneously after oxidative stress or deamination of proteins. Alternatively, aldehyde groups can be specifically generated by periodate oxidation of sugar residues of glycoproteins, for example antibodies. Antibodies can be oxidized by sodium periodate and labeled with Cyanine5.5 hydrazide to form Cyanine5.5 labeled antibodies. Since sugar residues in antibodies are located far from variable, epitope-binding site, this method is particularly good for the labeling of antibodies. Cyanine5.5 is a near infrared fluorophore, an analog of Cy5.5¨. It is particularly suitable for the applications which require low fluorescence background. The absorption and emission wavelength of the dye exhibit significant tissue penetration, so Cyanine5.5 is suitable for in vivo NIR imaging applications.

Catalog Number Product Size AVAILABILITY Price Qty
FLP392
Cy5.5 hydrazide, 1mg
1mg In stock
Regular Price:$110.00
FLP393
Cy5.5 hydrazide, 5mg
5mg In stock
Regular Price:$210.00
FLP394
Cy5.5 hydrazide, 25mg
25mg In stock
Regular Price:$410.00
FLP395
Cy5.5 hydrazide, 50mg
50mg In stock
Regular Price:$695.00
FLP396
Cy5.5 hydrazide, 100mg
100mg In stock
Regular Price:$1,190.00
Specifications

Product Type: Small Molecule
Chemical Formula: C40H46Cl2N4O
Molecular Weight: 669.73
Extinction Coefficient: 209000
Format: dark blue powder
Purity: NMR 1H, HPLC-MS (95%)
Solubility: moderate solubility in water, good in polar organic solvents (DMF, DMSO, alcohols)
Spectral Information: Excitation maximum, nm: 684
Emission maximum, nm: 710
CF260: 0.07
CF280: 0.03
Quantum Yield: 0.2
Storage: 24 months after receival at -20°C in the dark.
Shipped: room temperature

References

If you publish research with this product, please let us know so we can cite your paper.

Loading...