This rabbit IgG polyclonal antibody was generated against peptide and specific for mouse Osteopontin (SPP1).
Osteopontin is a phosphoglycoprotein synthesized in a variety of tissues and cells. It was originally identified as a bone matrix protein and subsequently as a cytokine produced by various immune and transformed cell lines. OPN is a biomarker for various types of cancers and inflammatory diseases. Excessive or dysregulated OPN expression has been linked to the pathogenesis of both autoimmune disorders such as multiple sclerosis, systemic lupus erythematosus, rheumatoid arthritis, atherosclerosis and other inflammatory diseases including cardiovascular disease, chronic obstructive pulmonary disease, inflammatory bowel disease, liver disease and asthma.
From the laboratory of Larry W. Fisher, PhD, National Institute of Dental and Craniofacial Research/NIH.
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|Antigen:||Osteopontin (SPP1), human|
|Molecular Weight:||32459 Da|
|Immunogen:||Recombinant E. coli|
|Tested Applications:||WB 1:2000, IHC 1:300|
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