CB1 Cannabinoid Receptor Expressing HEK293 Cell Lines

Human, mouse or rat cannabinoid receptor type 1 (CB1) expressing HEK293 cells.

Cannabinoid receptors are located throughout the body and are part of the endocannabinoid system. A major function of CB1 cannabinoid receptors expressed on neurons is to inhibit neurotransmission, often through a retrograde signaling system. CB1 receptors are involved in a variety of physiological processes including regulation of appetite, pain-sensation, mood, and memory. While CB1 cannabinoid receptors are one of the most abundant G protein-coupled receptors in the brain, they also found in many non-neuronal tissues including the liver, adipocytes, and some immune cells.

From the laboratory of Ken Mackie, MD, Indiana University.

Catalog Number Product DataSheet Size AVAILABILITY Price Qty
Mouse CB1 Cannabinoid Receptor Expressing HEK293 Cell Line
1 Vial In stock
Regular Price:$695.00
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Product Type: Cell Line
Cell Type: HEK293
Accession ID: P21554
Organism: Human, mouse or rat
Source: Embryonic Kidney
Morphology: Epithelial
Biosafety Level: BSL-2
Growth Conditions: DMEM, 10% FBS, (1mg/mL) G418, Pen/Strep (See PDF  Suggested Protocol for details)
Subculturing: 0.05% Trypsin-EDTA/Versene
Cryopreservation: 90% FBS, 10% DMSO
Comments: CB1 receptor has a N-terminus HA tag
Storage: Liquid nitrogen
Shipped: Dry Ice

From the laboratory of Ken Mackie, MD, Indina University.
  1. Daigle TL, Kearn CS, Mackie K. Rapid CB1 cannabinoid receptor desensitization defines the time course of ERK1/2 MAP kinase signaling. Neuropharmacology. 2008 Jan;54(1):36-44.
  2. Roger C, Buch C, Muller T, et al. Simultaneous Inhibition of Peripheral CB1R and iNOS Mitigates Obesity-Related Dyslipidemia Through Distinct Mechanisms [published online ahead of print, 2020 Jul 17]. Diabetes. 2020;db200078.  View article 

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