Tetrazine-Amine

Tetrazine-Amine demonstrates exceptionally fast cycloaddition kinetics with trans-cyclooctene (TCO) as the dienophile, the fastest kinetics ever reported for any bioorthogonal reaction. This reagent is supplied as HCl salt for improved stability and easy handling.

Tetrazine/TCOs are heterobifunctional reagents used for converting azido-containing peptides or protein into tetrazine-modified peptides or protein without the need for catalyst or axillary reagents. The inverse-electron demand Diels-Alder cycloaddition reaction of TCO with tetrazines is a bioorthogonal reaction that possesses exceptional kinetics (k > 800 -1s-1) and selectivity. Such excellent reaction rate constants are unparalleled by any other bioorthogonal reaction pair described to date.

Catalog Number Product DataSheet Size AVAILABILITY Price Qty
FCC656
Tetrazine-Amine, 25 mg
25mg In stock
Regular Price:$133.00
On Sale:
FCC657
Tetrazine-Amine, 100 mg
100mg In stock
Regular Price:$380.00
On Sale:
FCC658
Tetrazine-Amine, 500 mg
500mg In stock
Regular Price:$1,088.00
On Sale:
FCC659
Tetrazine-Amine, 1 G
1 G In stock
Regular Price:$1,711.00
On Sale:
Specifications

Product Type: Small Molecule
Chemical Formula: C9H9N5
CAS number: 1092689-33-2
Molecular Weight: 187.09
Variant MPN: 1130
Format: Pink solid
Purity: >95% (HPLC)
Solubility: DMSO, DMF
Storage: -20C. Desiccate
Shipped: Ambient

Documentation
References

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