TCO-PEG4-Acid is an amine-reactive, non-activated building block with enhanced solubility in aqueous media used for derivatizing amine-containing molecule in the presence of activators (e.g. EDC, or HATU) through a stable amide bond.

Tetrazine/TCOs are heterobifunctional reagents used for converting azido-containing peptides or protein into tetrazine-modified peptides or protein without the need for catalyst or axillary reagents. The inverse-electron demand Diels-Alder cycloaddition reaction of TCO with tetrazines is a bioorthogonal reaction that possesses exceptional kinetics (k > 800 -1s-1) and selectivity. Such excellent reaction rate constants are unparalleled by any other bioorthogonal reaction pair described to date.

Catalog Number Product Size AVAILABILITY Price Qty
TCO-PEG4-Acid, 25 mg
25mg In stock
Regular Price:$195.00
TCO-PEG4-Acid, 100 mg
100mg In stock
Regular Price:$550.00
TCO-PEG4-Acid, 500 mg
500mg In stock
Regular Price:$1,895.00

Product Type: Small Molecule
Chemical Formula: C20H35NO8
CAS number: N/A
Molecular Weight: 417.38
Variant MPN: 1088-25
Format: Colorless to slightly yellow oil
Purity: >95% (HPLC)
Solubility: DMSO, DMF, DCM, THF, Chloroform
Storage: Upon receipt store at -20C, desiccate
Shipped: Overnight


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