Methyltetrazine-PEG4-Acid is one of the most stable tetrazines commercially available. In addition to stabilization provided by the electron donating methyl group, the electron donating alkoxy substituent on the aromatic ring further improves the stability of Methyltetrazine-PEG4-Acid. The aqueous solubility of this reagent is substantially enhanced by a hydrophilic polyethylene glycol (PEG) spacer arm.

Tetrazine/TCOs are heterobifunctional reagents used for converting azido-containing peptides or protein into tetrazine-modified peptides or protein without the need for catalyst or axillary reagents. The inverse-electron demand Diels-Alder cycloaddition reaction of TCO with tetrazines is a bioorthogonal reaction that possesses exceptional kinetics (k > 800 -1s-1) and selectivity. Such excellent reaction rate constants are unparalleled by any other bioorthogonal reaction pair described to date.

Catalog Number Product DataSheet Size AVAILABILITY Price Qty
Methyltetrazine-PEG4-Acid, 25 mg
25mg In stock
Regular Price:$154.00
On Sale:
Methyltetrazine-PEG4-Acid, 100 mg
100mg In stock
Regular Price:$585.00
On Sale:
Methyltetrazine-PEG4-Acid, 500 mg
500mg In stock
Regular Price:$1,424.00
On Sale:

Product Type: Small Molecule
Chemical Formula: C20H28N4O7
CAS number: N/A
Molecular Weight: 436.56
Variant MPN: 1073
Format: Red crystalline
Purity: >95% (HPLC)
Solubility: DMSO, DMF, DCM, THF, Chloroform
Storage: -20C. Desiccate
Shipped: Ambient


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