Methyltetrazine-NHS Ester
Methyltetrazine-NHS Ester is an amine-reactive building block used for modification of amine-containing molecule in organic media. It reacts with primary amines (e.g., side chain of lysine residues or aminosilane-coated surfaces) at neutral or slightly basic pH to form covalent bonds. Short spacer arm adds minimal mass to modified molecules (230.2 daltons).
Tetrazine/TCOs are heterobifunctional reagents used for converting azido-containing peptides or protein into tetrazine-modified peptides or protein without the need for catalyst or axillary reagents. The inverse-electron demand Diels-Alder cycloaddition reaction of TCO with tetrazines is a bioorthogonal reaction that possesses exceptional kinetics (k > 800 -1s-1) and selectivity. Such excellent reaction rate constants are unparalleled by any other bioorthogonal reaction pair described to date.
Methyltetrazine-NHS Ester is an amine-reactive building block used for modification of amine-containing molecule in organic media. It reacts with primary amines (e.g., side chain of lysine residues or aminosilane-coated surfaces) at neutral or slightly basic pH to form covalent bonds. Short spacer arm adds minimal mass to modified molecules (230.2 daltons).
Tetrazine/TCOs are heterobifunctional reagents used for converting azido-containing peptides or protein into tetrazine-modified peptides or protein without the need for catalyst or axillary reagents. The inverse-electron demand Diels-Alder cycloaddition reaction of TCO with tetrazines is a bioorthogonal reaction that possesses exceptional kinetics (k > 800 -1s-1) and selectivity. Such excellent reaction rate constants are unparalleled by any other bioorthogonal reaction pair described to date.
| Catalog Number | Product | DataSheet | Size | AVAILABILITY | Price | Qty |
|---|
| Product Type: | Small Molecule |
| Chemical Formula: | C15H13N5O4 |
| CAS number: | 1644644-96-1 |
| Molecular Weight: | 327.29 |
| Variant MPN: | 1128 |
| Format: | Red crystalline |
| Purity: | >95% (HPLC) |
| Solubility: | DMSO, DMF |
| Storage: | -20C. Desiccate |
| Shipped: | Ambient |
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