The stability of Methyltetrazine-Amine is substantially improved compared to hydrogen substituted Tetrazine-amine. Superior stability of Methyltetrazine-Amine allows this reagent to be used in wider range of chemical transformations. Long-term storage of Methyltetrazine-Amine, especially in aqueous buffer, is also greatly improved compared to Tetrazine-Amine. This reagent is supplied as HCl salt for improved stability and easy handling.
Tetrazine/TCOs are heterobifunctional reagents used for converting azido-containing peptides or protein into tetrazine-modified peptides or protein without the need for catalyst or axillary reagents. The inverse-electron demand Diels-Alder cycloaddition reaction of TCO with tetrazines is a bioorthogonal reaction that possesses exceptional kinetics (k > 800 -1s-1) and selectivity. Such excellent reaction rate constants are unparalleled by any other bioorthogonal reaction pair described to date.
|Product Type:||Small Molecule|
|Storage:||Upon receipt store at -20C|
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